Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
Get full text
Get full text
Get full text

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”

Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …”

Pharmacist input to depression screening and management in patients with diabetes: a systematic review by Mai I. AL‑Hawamdeh (22798782)

“…All studies demonstrated the positive impact of pharmacists on depression screening, treatment initiation, and medication adherence., Some interventions failed to significantly improve clinical parameters such as HbA1c levels or depressive symptoms. …”

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”

Non-Invasive Biomarkers for Early Lung Cancer Detection by Harman Saman (16316283)

“…<p dir="ltr">Worldwide, lung cancer (LC) is the most common cause of cancer death, and any delay in the detection of new and relapsed disease serves as a major factor for a significant proportion of LC morbidity and mortality. …”

Hepatoprotective activity of the wild carrot chloroform-based fraction against CCl4-induced liver toxicity in mice by Shebaby, W.

“…Pretreated groups with chloroform-based fraction reduced significantly the serum levels of AST and ALT. It also reversed the CCl4-induced decrease in SOD, CAT and GST levels thereby reducing significantly hepatic damage. …”
Get full text
Get full text
Get full text
Get full text

The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France by Harakeh, Mostafa

“…As a result of the lower levels of earnings management and information asymmetry, we predict and find that the market reaction to issuing SEOs improves significantly for high-divergence firms following IFRS. …”
Get full text
Get full text
Get full text
Get full text

Three cases of chronic photodermatitis successfully treated with upadacitinib by Hissa Al-Marri (22827287)

“…Here, we report three cases of chronic photodermatitis treated with upadacitinib, a selective Janus kinase 1 inhibitor, as monotherapy, which resulted in fast, significant and sustainable improvement of signs and symptoms, with a favourable safety and tolerability profile.…”

Osteoporosis: An under-recognized public health problem by Rajasree Vijayakumar (19807284)

“…Therefore, improved awareness of the disease may influence personal habits, reduce suffering, and alleviate the burden on healthcare expenditure.…”

Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment by Alanod D. AlQahtani (18805930)

“…<p>Protein therapeutics play a significant role in treating many diseases. They, however, suffer from patient’s proteases degradation and antibody neutralization which lead to short plasma half-lives. …”

Predictors of Mortality in Veno-Arterial Extracorporeal Membrane Oxygenation Regardless of Early Left Ventricular Unloading: A National Experience by Alaa Rahhal (14150403)

“…The significant positive predictors of mortality with VA-ECMO regardless of IABP in CS were CPR > 20 minutes (aOR 14.74, 95% CI 2.02-107.41; p-value= 0.008), older age (i.e., greater than 55 years) and LM disease of more than 50% stenosis were associated with a fourfold increase in the odds of mortality while on VA-ECMO. …”

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…Bisulfite-sequencing demonstrated 45.6% demethylation efficiency at the NY-ESO-1 gene promoter region and RT-qPCR analysis confirmed the significant induction of NY-ESO-1 at mRNA level (128-fold increase, *p < 0.050). …”

Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study by Zeana, Samir AlKudsi

“…Fear of COVID-19 was a statistically significant and an independent predictor of depression, anxiety, and stress levels. …”
Get full text
Get full text
Get full text

Chiropractic manipulations gone wrong by Nature Research (16552612)

“…Blood accumulates between the layers of the artery’s wall, obstructing blood flow and potentially forming clots. This, in turn, decreases the blood supply to the brain, causing stroke. …”

The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere by Sara H. Al-Hadidi (17821196)

“…Using the highest amounts of biofertilizer and chemical fertilizer decreased the species diversity within the samples. …”

Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy by Palavecino, Martin

“…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …”
Get full text
Get full text
Get full text

Occupational Violence at Lebanese Emergency Departments by Dimassi, Hani

“…Exposure to verbal abuse was associated with serious outcomes including significantly higher levels of occupational burnout and an increased likelihood to quit current job. …”
Get full text
Get full text
Get full text

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

“…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …”
Get full text

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …”
Get full text
Get full text
Get full text