Natural products as chemo-radiation therapy sensitizers in cancers by Sabah Nisar (12561961)

“…<p dir="ltr">Cancer is a devastating disease and is the second leading cause of death worldwide. …”

FoxP3⁺ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets by Reem Saleh (3513056)

“…We also describe potential therapeutic strategies to target Tregs in combination with other types of immunotherapies aiming to overcome tumor resistance and improve clinical outcomes in cancer patients. Overall, understanding the prognostic significance of FoxP3⁺ Tregs in various cancers and their contribution to therapy resistance could help in the development of more effective targeted therapeutic strategies to enhance the clinical outcomes in cancer patients.…”

Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment by Christos Fountoukis (4722963)

“…The use of the local emissions allowed for a significant improvement in the representation of air quality levels in the city. …”

Successful bone marrow transplantation in a patient with Omenn syndrome, a rare variant of severe combined immunodeficiency syndrome: A case report by Ubaid Khan (12476186)

“…Emphasis on newborn screening and multidisciplinary care improves outcomes for infants with inherited disorders. …”

Systematic review and meta-analysis of performance of wearable artificial intelligence in detecting and predicting depression by Alaa Abd-Alrazaq (17430900)

“…Subgroup analyses revealed that there is a statistically significant difference in the highest accuracy, lowest accuracy, highest sensitivity, highest specificity, and lowest specificity between algorithms, and there is a statistically significant difference in the lowest sensitivity and lowest specificity between wearable devices. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Overexpression of FOXA2 reversed the defective phenotypes and improved hepatocyte functionality in iPSC-derived hepatic cells lacking FOXA2. …”

Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden by Farra, Anna

“…Cotrimoxazole resistance has also been increasing significantly in most hospitals, in spite of decreasing sales of cotrimoxazole and trimethoprim. …”
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Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses by Mohammed I., Danjuma

“…BackgroundDespite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine in patients with Coronavirus Disease 2019 (COVID-19) clinical syndrome. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …”
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The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …”

Impact of Stapedectomy on Tinnitus Severity and Hearing Outcomes in Patients With Otosclerosis: A Systematic Review by Noora Al Hail (23073583)

“…Most patients experienced significant improvement within 6 months.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Ear, Nose & Throat Journal<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1177/01455613251382671" target="_blank">https://dx.doi.org/10.1177/01455613251382671</a></p>…”

Natalizumab Treatment for Relapsing Multiple Sclerosis Stabilises Normal-Appearing White Matter Microstructure: A One-Year Prospective Ultra-High-Field Quantitative Imaging Study by Radu Tanasescu (439168)

“…The difference in the T1 relaxation times at month 6 and month 12 of natalizumab treatment was not significant, suggesting the lack of accumulation of tissue damage, while improvements were seen in MTR (MTRAPT and MTRNOE measures) at month 12, suggesting a tissue repair effect. …”

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort by Mohamed Adil Shah Khoodoruth (14589828)

“…Key measurements included complete blood count, lipid panel, HbA1c, and ferritin levels. Our findings indicated elevated body mass index (BMI) and triglyceride (TG) levels in both patient groups compared to controls. …”

Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats by Maisa Siddiq Abduh (16381125)

“…Moreover, levels of Capase-3, and cytochrome C were significantly reduced by THYO or IL35, while, levels of Bcl-2 were markedly increased. …”

Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq by Dujaili, Juman Abdulelah

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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We characterized variants in <i>CCL5</i> and that of six other CCL5 signaling genes (<i>CCND1, ZMIZ1, CASP8, NOTCH2, MAP3K21, and HS6ST3</i>) among 1,082 unrelated Tunisian subjects (544 BC patients, including 196 TNBC, and 538 healthy controls), assessed the association of the variants with BC-specific overall survival (OVS) and progression-free survival (PFS), and correlated CCL5 mRNA and serum levels with <i>CCL5</i> genotypes. We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Harnessing Qatar Biobank to understand type 2 diabetes and obesity in adult Qataris from the First Qatar Biobank Project by Ehsan Ullah (2698921)

“…One of the aims of Qatar Biobank is to improve the understanding and treatment of common diseases afflicting Qatari population such as obesity and diabetes.…”

Why does the adverse effect of inappropriate MRI for LBP vary by geographic location? An exploratory analysis by Mujahed Shraim (14153145)

“…Targeted healthcare and work disability prevention interventions may improve work disability outcomes in patients with occupational LBP.…”

Artificial Intelligence and Machine Learning Applications in Sudden Cardiac Arrest Prediction and Management: A Comprehensive Review by Sarah Aqel (17787809)

“…Deep learning is gaining prominence in radiomics and population health for disease risk prediction. There’s a significant focus on the integration of AI and ML in prehospital emergency care, particularly in using ML algorithms for predicting outcomes in COVID-19 patients and enhancing the recognition of out-of-hospital cardiac arrest (OHCA). …”

Gene therapy for spinal muscular atrophy: the Qatari experience by Hossamaldein Gaber Ali (14152632)

“…Furthermore, one event of vomiting after infusion was reported in one patient. Significant improvements in CHOP INTEND scores were observed following therapy. …”