The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …"

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

"…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. We postulate that epigenetic factors contribute to the observed variability in intellectual disability, as well as at the level of neurodegeneration seen in T21 individuals.…"

RFX3 is essential for the generation of functional human pancreatic islets from stem cells حسب Bushra Memon (4792767)

"…This was supported by our findings of high EC marker expression levels in <i>RFX3</i> KO EPs and islets. In addition, RFX3 loss led to smaller islet organoids, elevated thioredoxin-interacting protein levels and increased apoptosis in EPs and islets. …"

Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies حسب Chiara Cugno (3441302)

"…<p>Rosiglitazone is an effective insulin-sensitizer, however associated with bone loss mainly due to increased bone resorption and bone marrow adiposity. …"

OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... حسب Pia Tohme Khalaf (17425551)

"…The couple's relationship quality also plays a significant role, with secure romantic attachment positively influencing prenatal attachment and promoting resilience in times of stress, while avoidant or anxious romantic attachment can lead to lower prenatal bonding and increased pregnancy-related worries.…"

Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge حسب ALMUTAWA, MUBARAK

"…The findings show there is no set up/adjustment and speed losses. Moreover, breakdown losses were 2.2% for first extruder and 6.06% for second extruder, and decreased quality losses were 1.28% for first extruder and 2.8% for second extruder for the study of six significant losses (which became three big losses due to speed losses and set up/adjustment do not exist).…"
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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development حسب Al Saneh, Mounir

"…Our results showed that there is no difference in viability of the VWS patient cells compared to healthy control cells. However, a significant decrease in the migratory and adhesion ability of the VWS patient cells was detected compared to the control, which could account for the phenotype. …"
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Effectiveness of 2D magnesium phosphate hydrogel for surgical decontamination of dental implants: A case series حسب Sara Behmanesh (22391968)

"…The findings revealed a statistically significant decrease in probing depth, bleeding on probing, and the number of exposed implant threads following treatment with the magnesium phosphate hydrogel, though the exact role of the hydrogel in these improvements warrants further exploration.…"

Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study حسب Spencer L James (8673927)

"…</p><h3>Results</h3><p dir="ltr">Globally, there were 8 991 468 (7 481 218 to 10 740 897) new fire, heat and hot substance injuries in 2017 with 120 632 (101 630 to 129 383) deaths. At the global level, the age-standardised mortality caused by fire, heat and hot substances significantly declined from 1990 to 2017, but regionally there was variability in age-standardised incidence with some regions experiencing an increase (eg, Southern Latin America) and others experiencing a significant decrease (eg, High-income North America).…"

Development and Testing of Novel Drilling Fluids Using Fe2O3 and SiO2 Nanoparticles for Enhanced Drilling Operations حسب Vryzas, Zisis

"…The rheological analysis showed an increase of the yield stress and of the gel strength as the concentration of nanoparticles was increased. …"
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Characterization and cytotoxicity assessment of nargile smoke using dynamic exposure حسب Khalil, Christian

"…Microscopical analysis showed a systematic increase in cell rounding post exposure indicating cellular loss of adhesion and potential membrane damages. …"
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Effects of Autonomous Vehicles on the Signalized Intersections’ Performance حسب Noaman, Mahmoud Atef

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The effectiveness of Brain Gym® Exercises on Improving Students’ Performance in classes of middle school boys in private schools in Dubai, UAE(Ethnographic Study Conducted at the A... حسب AL HERBAWI, DUA’A

"…On the academic level, the marks of post-implemented quizzes showed a significant drop, however, post-implemented major exams showed a significant rise. …"
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Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

"…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent حسب Nasreddine, Ghenwa

"…[HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. This indicates that the activation of autophagy following arginine-deprivation, rather than being protective, mediates cell cytotoxicity leading to death by autophagy.…"
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Content-Aware Adaptive Video Streaming Using Actor-Critic Deep Reinforcement Learning حسب Amer, Hala Nagi

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Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties حسب Mohammed, Alsafran

"…In contrast, alkali-treated fibers showed a significant decrease in radical scavenging activity (almost 7–8 fold) and reducing power potential (6-fold) and exhibited no antifungal activity, potentially due to the loss of bioactive components such as lignin and essential oils. …"
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Orofacial Clefts حسب El Baba, Nada

"…The striking difference in behavior was related to cell migration, whereby the patient-derived cells showed decreased motility, increased adhesion, and a general loss of polarity compared to the healthy cells. …"
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…Liver resection has been used increasingly in the last 20 years, and mortality rates associated with the procedure are less than 5% at high-volume centers.1, 2 and 3 The safety of liver resection is in part the result of the development of techniques aimed at reducing blood loss. …"
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Effect of Diverse Seismic Hazard Estimates on Performance and Overall Cost of RC Shear Wall Buildings in Dubai, UAE حسب Aly, Nader Essam

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