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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”
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122
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
Published 2018“…It also significantly decreased the levels of pro-caspase-3, p53, Bcl-2, p-Erk/Erk and p-Akt/Akt and increased p21 and Bax proteins. …”
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123
Enhancing Organisational Transparency through Talent and Performance Management
Published 2011“…Therefore, this study suggests a triangular link between talent management, performance management, and organisational transparency in the sense that a significant increase in organisational performance and talent management could increase employees’ trust. …”
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124
STARD 13 in prostate cancer. (c2018)
Published 2018“…In this study, we investigate the role of StarD13, an inhibitor of RhoA and Cdc42 through its GAP activity, on prostate cancer cells proliferation and metastasis by manipulating its level of expression in the cells. Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …”
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125
Implications on Educational Management During the COVID-19 Pandemic
Published 2021“…Education sector faced a significant transition recently, shifting from face-to-face classes to online classes due to the unprecedented COVID-19 pandemic. …”
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126
Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
Published 2016“…We deployed artificial vegetation with 4 different interstructural space widths (complexities): 6, 10, 14 and 27 mm. At the high levels of habitat complexity used in this study, the main effect of increasing complexity was excluding beetles from higher complexity treatments, particularly larger beetle species. …”
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127
Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways
Published 2022“…Treatment of rats with Pb for three consecutive days significantly increased the accumulation of Pb in lung tissues causing severe interstitial inflammation. …”
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128
Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
Published 2018“…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …”
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129
Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients
Published 2019“…We found a significant increase in the levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …”
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130
Impact of transcranial alternating current stimulation on psychological stress: A functional near-infrared spectroscopy study
Published 2025“…The results revealed significant hemodynamic changes and reduced stress levels in the tACS group compared to the sham group (p < 0.001). …”
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Metaverse and financial markets: A quantile-time-frequency connectedness analysis
Published 2024“…The results highlight a significant increase in connectivity during extreme conditions compared to median levels. …”
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133
Implications on Educational Management During the COVID 19 Pandemic
Published 2021“…Education sector faced a significant transition recently, shifting from face-to-face classes to online classes due to the unprecedented COVID-19 pandemic. …”
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FoxP3<sup>+</sup> T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
Published 2020“…Proportions of Tregs in the peripheral blood of some cancer patients increase by approximately two-fold, compared to those in healthy individuals. …”
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136
Rapid separation of very low concentrations of bacteria from blood
Published 2017“…These results show that this rapid technique recovers a significant amount of bacteria from blood containing clinically relevant low levels of bacteria, producing the bacteria in minutes. …”
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137
Community formation in socially enabled wireless networks. (c2018)
Published 2018“…D2D leverages prevalent low-power and ISM-band technologies to augment existing infrastructure-based wireless systems to achieve significant increase in effective bit rates. There exist, nonetheless, various challenges that hinder the proliferation of D2D communications in public settings mainly due to interference, privacy and trust concerns. …”
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masterThesis -
138
From Integrity to Inflation: Ethical and Unethical Citation Practices in Academic Publishing
Published 2025“…A quantitative analysis of self-citation practices across different countries and fields revealed significant disparities, with some nations exhibiting high levels of self-citation among top scientists, while others showed more restrained behaviors. …”
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139
Opportunities for Knowledge Sharing, Knowledge Transfer, and Innovation in the UAE through Academia-Industry Collaboration
Published 2013“…Competition and technological changes continue to increase at a rapid rate which leads to a significant growth in the need for connection between firms and universities, not only to discover knowledge but also to achieve improvements in performance. …”
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140
Exploring the Critical Success Criteria and Factors of Adopting Technological Innovation in the U.A.E Public Sectors
Published 2016“…In addition, managerial supports for the innovative projects in the U.A.E federal department succeeded to increase the level of satisfactions for the project team members. …”
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