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541
Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling
منشور في 2020"…Even though WTS initially decreased anxiety-like behaviors, prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. Finally, we showed that nicotine mediates the effects of WTS only on resilience to stress by increasing BDNF and TRKB levels and signaling. …"
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article -
542
Industrial Processes Performance Improvement using Six Sigma Principles and Tools
منشور في 2019"…The process improvement with Six Sigma resulted to 99.7 % quality percentage which is 0.02% away from Sigma level. Moreover, there has been a significant waste reduction and operational efficiency, which has greatly reduced the cost of operation and better customer retention. …"
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543
Determinants of Domestic Workers' Employment
منشور في 2012"…Controlling for household, household head, dwelling, and regional characteristics, we find that the probability of hiring a domestic worker is significantly higher for larger households, female headed households, larger dwellings, and increases with aggregate household consumption. …"
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conferenceObject -
544
The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
منشور في 2024احصل على النص الكامل
doctoralThesis -
545
Organizational climate and its effects on the employees commitment
منشور في 2011"…Moreover, normative commitment is significantly related with three organizational climates: rewards, warmth and support, and expect approval. …"
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article -
546
Content-Aware Adaptive Video Streaming Using Actor-Critic Deep Reinforcement Learning
منشور في 2024احصل على النص الكامل
doctoralThesis -
547
The retention of health human resources in primary healthcare centers in Lebanon
منشور في 2012"…Regression analysis revealed that high levels of burnout, lower level of education and low tenure were all associated with increased likelihood to quit. …"
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article -
548
A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells
منشور في 2008"…Moreover, CD3+ T cells exhibited markedly enhanced levels of phosphorylated ZAP-70, a critical proximal signal in T cell activation, after exposure to WP1066. …"
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article -
549
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"
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550
Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
منشور في 2023"…Moreover, tranexamic acid (TXA) use (n = 106) in surgery reduced hospital stays, tourniquet time, drain output, and increased pre- and postoperative haemoglobin and hematocrit levels compared to no TXA group (n = 156) (p < 0.05, z-score reported).…"
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551
The effects of Organisational Ambidexterity and New Public Management on Public Sector Service Quality through Service Innovation
منشور في 2020"…Moreover, the bureaucratic structure of the public sector hinders any initiative to improve, meet the demand for better products and services and operate without necessarily increasing its expenditures and disbursements. Hence, the need to reduce bureaucracy may give rise to the increasing demand for service innovation to attain service quality and enhance performance. …"
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552
Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation
منشور في 2015"…Aspect ratio and size were both significantly higher in DMEM (p<0.01). The level of expression of α-SMA was significantly reduced in fibroblast media at day 2 after isolation (p<0.01) and the expression of α-SMA, SM22 and EDA-fibronectin was significantly reduced in fibroblast media at days 7 and 12 post-isolation (p<0.01). …"
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553
E-cigarettes in the Middle East: The known, unknown, and what needs to be known next
منشور في 2023"…The prevalence of electronic cigarettes (e-cigarettes) is increasing globally. Population-level data from several nations suggest that a higher proportion of youth and young adults are using e-cigarettes compared to the general population. …"
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article -
554
Profiling the autoantibody repertoire reveals autoantibodies associated with mild cognitive impairment and dementia
منشور في 2023"…And 20 proteins had significantly altered autoantibody responses in MCI compared to cognitively normal individuals. …"
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555
Deep Learning for the Accurate Prediction of Triggered Drug Delivery
منشور في 2024"…The model accurately predicts drug release from liposomes and MOFs under various conditions, including low- and high-frequency ultrasound (extrinsic triggering), microwave exposure (extrinsic triggering), ultraviolet light exposure (extrinsic triggering), and different pH levels (intrinsic triggering). The deep learning-based predictions significantly outperform linear predictions, proving the utility of advanced computational methods in drug delivery. …"
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article -
556
Enhancing the Main Contractor-Subcontractor trusting relationship in the United Arab Emirates: A strategic approach to rebuilding trust in complex construction projects
منشور في 2017"…The researcher found that trust factor has a significant impact on subcontractors and main contractors’ relationship, however, there is minor impact of their relationship on building trust between them, and that early contractor engagement in the initiation and planning stage positively impacts the subcontractors and main contractors’ relationship, and that the higher the level of trust between them, the better the project performance. …"
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557
Willingness to Pay for Clean Air: Evidence from the UK
منشور في 2023"…The willingness to pay for clean air is also significant and increases with level of education. These measurements derived can be used as benchmarks for pollution abatement subsidies or pollution taxes and can help in projecting a more comprehensive assessment of costs and benefits.…"
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bookPart -
558
Developing an Urban Resilience Index for Ajman City
منشور في 2023"…One of the issues raised was that the population of urban areas has grown significantly in recent years, and is expected to grow even further. …"
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559
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
منشور في 2019"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"
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560
Unsustainability in emergent systems
منشور في 2017"…These challenges are already significant enough to seriously hamper the network's ability to deliver an acceptable level of service within reasonable norms for environmental, health and safety impacts, especially in and around the country's major urban centers. …"
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conferenceObject