Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy حسب Samson Mathews Samuel (18808246)

"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"

Doping in sports and current regulations حسب Muneera Ahmed Alkhelaifi (21347873)

"…Moreover, in order to fight this phenomenon, local and international laws should penalize athletes who are engaged in doping at various levels. This criminal offense charges should implement prison sentence as well as imposing significant fine amounts to be paid. …"

Enhancing sustainability through resource efficiency in beef production systems using a sliding time window-based approach and frame scores حسب Muhammad Ismail (3176079)

"…Collectively, this increases the need to enhance sustainability in the beef sector. …"

A Novel Hybrid Physical-Layer Authentication Scheme for Multiuser Wireless Communication Systems حسب Elmehdi Illi (19368673)

"…<p dir="ltr">Guaranteeing decent secrecy levels in future wireless network generations has gained crucial importance due to the unprecedented increase in wireless connectivity worldwide. …"

Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation حسب Najma Latif (250130)

"…Aspect ratio and size were both significantly higher in DMEM (p<0.01). The level of expression of α-SMA was significantly reduced in fibroblast media at day 2 after isolation (p<0.01) and the expression of α-SMA, SM22 and EDA-fibronectin was significantly reduced in fibroblast media at days 7 and 12 post-isolation (p<0.01). …"

Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden حسب Farra, Anna

"…Ciprofloxacin resistance increased (p &lt; 0.001) in parallel. Quinolone use increased until 1992; subsequently, sales have remained at a stable level. …"
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Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat حسب Kanbar, Roy

"…Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unaltered (P = 0.680, repeated-measures ANOVA). …"
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Unveiling Teachers’ Instructional Self-efficacy in Science, Mathematics, and Technology: Personal and Contextual Influences حسب Abdellatif Sellami (14147922)

"…Results indicate that, despite teachers’ high self-efficacy in STEM instruction, significant differences were observed across gender, school type, educational level taught, and academic degree achieved. …"

Unveiling Teachers’ Instructional Self-efficacy in Science, Mathematics, and Technology: Personal and Contextual Influences حسب Abdellatif Sellami (14147922)

"…Results indicate that, despite teachers’ high self-efficacy in STEM instruction, significant differences were observed across gender, school type, educational level taught, and academic degree achieved. …"

Prevalence, Associated Risk Factors, and Adverse Cardiovascular Outcomes of Statins Discontinuation: A Systematic Review حسب Shahd A. Ageeb (22047824)

"…Five studies that reported the cardiovascular risk of statin discontinuation within the first year of initiation showed significantly increased risk of discontinuation, including all‐cause mortality (hazard ratio: 1.36–3.65).…"

Characteristics and health implications of fine particulate matter near urban road site in Islamabad, Pakistan حسب Sabir Hussain (1332675)

"…The results from the <u>Inductively Coupled Plasma Atomic Emission Spectroscopy </u>(ICP-OES) indicated a gradual increase in the total elemental composition of PM2.5 from autumn to winter, maintaining high levels throughout the winter season. …"

Impacts of COVID-19 pandemic on environment, society, and food security حسب Hafiz Mohkum Hammad (17541432)

"…COVID-19 affected all sections of the population, particularly the most vulnerable members of society, and thus pushed more people into poverty. At the world level, it increased risks to food safety by increasing prices and lowering revenues, forcing households to reduce their food consumption in terms of quantity and quality. …"

Influence of proton pump inhibitors on gastritis diagnosis and pathologic gastric changes حسب Nasser, Soumana C.

"…Multivariate analysis has also demonstrated that in the presence of previous PPI exposure (OR = 0.217, 95%CI: 0.123-0.385), GERD (OR = 0.317, 95%CI: 0.132-0.763, P = 0.01), alcohol intake (OR = 0.396, 95%CI: 0.195-0.804, P = 0.01), the detection of H. pylori was less likely. Chronic use of PPIs may mask H. pylori infections promoting the diagnosis of non-H. pylori gastritis and leads to a significant drop in H. pylori densities and to an increased risk of intestinal metaplasia. …"
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SGLT-2 inhibitors associated euglycemic and hyperglycemic DKA in a multicentric cohort حسب Fateen Ata (12217764)

"…In T2D patients on SGLT2i, infection is probably associated with an increased risk of developing EuDKA. The differential role of individual SGLT2i analogs is less clear and will need exploration by more extensive prospective studies.…"

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Furthermore, the combination therapy upregulates protein expression levels of pro-apoptotic proteins Bax, p53 and cytochrome c, downregulates the expression of antiapoptotic Bcl-2 protein and increases the cleavage of procaspases 8 and 9; this suggests that the combination activates apoptosis via both the intrinsic and extrinsic pathways. …"
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions حسب Mansour, Hanine

"…Objective: To determine the effect of a computerized pharmacy alert on the number of adverse events related to hyperkalemia in a hospital setting and to study the impact of guidelines and education on pharmacist response to high potassium levels. Methods: An alert was built into the pharmacy computer system, which warned pharmacists about a potassium level greater than 5.1 mEq/L when processing an order that could increase potassium. …"
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Airflow dynamics in an emergency department: A CFD simulation study to analyse COVID-19 dispersion حسب Odi Fawwaz Alrebi (19499188)

"…The analysis revealed that three critical areas of the emergency department, namely overnight patient beds, operating rooms, and resuscitation rooms, had significantly higher air velocity, dispersion, and mixing levels than the rest of the department's spaces. …"

Analyzing hydrodynamic changes in the Dubai Creek: a pre- and post-extension study حسب Elkersh, Khaled

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Assessment of Disinfection By-Product Formation in Polymeric Pipe Distribution Systems حسب Shabani, Sina

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Rising blood pressure in Bangladesh حسب Nature Research (16552612)

"…People aged 66 to 74 were found to be significantly more at-risk than those in other age groups. …"