Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien... by Shayista Akbar (14442117)

“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”

The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells by Fayad, Christelle

“…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …”
Get full text
Get full text
Get full text

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…The highest level of leaders makes fewer conceptual errors, and these errors increase as the levels decrease. …”
Get full text

Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation by Feng, Samuel

“…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …”
Get full text
Get full text

Polarimetric SAR Speckle Reduction by Hybrid Iterative Filtering by Yahia, Mohamed

“…Speckle filtering in synthetic aperture radar polarimetry (PolSAR) is essential for the extraction of significant information. In this study, the authors introduced a hybrid iterative filtering scheme. …”
Get full text

A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media by Shaheeda Marakkar Anangadan (19239607)

“…However, when accounting for leaching, which was significant in some organic media but expected to decrease with time, most organic media (SCG, date seeds, coco coir and bone) achieved around 80 % TOC removal. …”

Determinants of Disordered Eating Patterns among an LGTBQ Community in Lebanon by Harb, Hana

“…Generally, the LBGTQ population in this study scored higher than cisgender and heterosexual individuals for the mean and global scores of the EDE-Q, indicating an increased risk for disordered eating behaviors and attitudes. …”
Get full text
Get full text
Get full text

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.) by Muhammad Fasih Khalid (10652246)

“…The maximum decrease in photosynthetic machinery, plant growth attributes (shoot length, root length, no. of leaves, fresh and dry biomass (shoot and root)), and more accumulation of Hg in leaves, roots, and fruits of sweet pepper. Additionally, SA significantly reduced the reduction in photosynthetic attributes and plant growth, and increased antioxidant enzymes (SOD, POD, and CAT) under Hg toxicity. …”

Influence of hosting the world’s most popular football competition on Response and Transport Time of Ground Emergency Ambulances in Qatar by Reem Bassam Tluli (18505131)

“…<h3>Background</h3><p dir="ltr">Qatar was anticipating approximately 1.2 million visitors during the FIFA World Cup 2022TM, significantly increasing the population, road traffic1 , and the number of emergency calls received,2 which could potentially affect the response and transportation times of emergency ambulances. …”

Sustainable food development for societies in hot arid regions: Thermoeconomic assessment of passive-cooled soil-based and hydroponic greenhouses by Omer Abedrabboh (17346847)

“…Moreover, heat waves and increasing average ambient temperatures have significantly increased plants' dehydration and death. …”

Lead exposure of Bangladeshi women at childbearing age: Does mother's education reduce fetal risk factors? by Sharmind Neelotpol (19732277)

“…Depending on its concentration in the body, lead may cause lower IQ level, autism, abnormal pregnancy outcome, abortion, and increased involvement in crime. …”

Enterprise risk management in healthcare organizations by SAJWANI, REHAB

“…However, different levels of agreement of each independent variable to dependent variable indicate different levels of contribution of each organizational factor on effective implementation of ERM. …”
Get full text

Giving anaemic cardiac surgery patients a better chance by Nature Research (16552612)

“…There was, however, a significant difference between the two groups in terms of mortality. …”

Sustainable Consumption and Education for Sustainability in Higher Education by Shaikha R. Al-Nuaimi (19488232)

“…An exploration into consumer behaviors on an individual and contextual level is presented, highlighting key factors for achieving sustainable consumption on the consumer level. …”

STARD 13 in prostate cancer. (c2018) by Saab, Sahar S.

“…In this study, we investigate the role of StarD13, an inhibitor of RhoA and Cdc42 through its GAP activity, on prostate cancer cells proliferation and metastasis by manipulating its level of expression in the cells. Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …”
Get full text
Get full text
Get full text

Implications on Educational Management During the COVID-19 Pandemic by Alfalasi, Khulood

“…Education sector faced a significant transition recently, shifting from face-to-face classes to online classes due to the unprecedented COVID-19 pandemic. …”
Get full text

The safety of outpatient total shoulder arthroplasty: a systematic review and meta-analysis by Abdulaziz F. Ahmed (14150082)

“…<h2>Purpose</h2> <p>To meet the increasing demands of total shoulder arthroplasty (TSA) while reducing its financial burden, there has been a shift toward outpatient surgery. …”

Metaverse and financial markets: A quantile-time-frequency connectedness analysis by Ahmet Faruk Aysan (11902115)

“…The results highlight a significant increase in connectivity during extreme conditions compared to median levels. …”

Enhanced natural convection in a U-shaped baffled cavity: Synergistic effects of magnetic fields and wall oscillations on Nano-encapsulated PCM by Ahmed M. Hassan (8893106)

“…Results show that the Rayleigh number has the most significant impact, increasing the time-averaged Nusselt number by 129.8 % as <i>Ra</i> rises from 10³ to 10⁵. …”