Image 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.pdf by Ana Virseda-Berdices (9638081)

“…Ten and five of these upregulated genes were classified into two significantly enriched KEGG pathways: cell cycle and progesterone-mediated oocyte maturation (q-value <0.05), respectively. …”

Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 3_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc by Shujun Tan (20011518)

“…</p>Results<p>The global burden of NE has significantly declined over the past three decades. Between 1990 and 2021, the global ASIR decreased from 20.22 to 17.16, while the number of cases fell from 1,295,891.1 to 1,061,448.15, reflecting an 18.09% reduction. …”

Demographic characteristics of participants. by Maryam Rafiee (10368504)

“…Furthermore, an increase of one point in work ability score leads to a decrease in WMSDs in the neck, wrists/hands, low back and hips/thighs regions by 13.5%, 8%, 11.5%, and 9%, respectively.…”

Image 2_One-year post lockdown trajectories of mental health and impact of COVID-19 lockdown-related factors.jpeg by Mathilde Mongeau (20864315)

“…</p>Results<p>Our analysis revealed a significant decrease in the proportion of individuals experiencing poor mental health (elevated GAD-7 or PHQ-9 > 4) from lockdown period to 1 month and 6 months post-lockdown. …”

DataSheet1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic... by Boris Jakopovic (9265517)

“…Even with treatment advancements, the survival rates for these patients remain suboptimal. There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …”

<i>Wigglesworthia</i> and <i>Sodalis</i> density in mated dsCPT1(treatment) compared to dsGFP (control) treated Gmm at the end of their 4^th GC. by Brian L. Weiss (7225103)

“…While this treatment did significantly decrease <i>Sodalis</i> density, this bacterium, unlike <i>Wigglesworthia</i>, has no documented impact on tsetse fecundity.…”

Critical period EB odorant experience via Or42a neurons specifically elevates VM7 serotonin signaling. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparisons show a significant increase in serotonin (<i>n</i> = 12/condition, <i>p</i> = 7.13 × 10⁻⁵) and a significant decrease in VM7 innervation (<i>n</i> = 12/condition, <i>p</i> = 4.78 × 10⁻¹⁰) with EB experience. …”

Baseline firing rate: locomotion speed control and the effect of behavioral context on negative preferring neurons. by Yun Wen Chu (20968520)

“…(<b>E</b>) Bar graph of the percent of neurons that significantly increase, decrease, or do not change during the Miss or Away condition. …”

Data Sheet 1_Can posttreatment blood inflammatory markers predict poor survival in gynecologic cancer?: a systematic review and meta-analysis.xlsx by Minyong Choi (22465405)

“…Early sampling of within one month after treatment completion (≤ median 15 days) showed prognostic significance (pooled hazard ratios 3.43–3.55; p < 0.0001), whereas late sampling demonstrated no significant associations. …”

Data Sheet 1_Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.pdf by Elena Campione (8906858)

“…Finally, improvements in clinical scores i.e., PASI, NAPSI, DLQI, itch VAS, PAIN VAS, scPGA and sPGA-G and biochemical serum profile, as well as a significant decrease in serum IL-17A, TGF-β 1 and IL-10 levels (from 8.51 to 4.16 pg/mL; from 66.10 to 48.70 ng/mL and from 20.05 to 14 pg/mL, respectively) were observed in all patients.…”

Image 4_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Image 2_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Table_1_Spatiotemporal variation in grain production performance and efficiency of the cultivated landscapes in Upper Blue Nile Basin of Ethiopia: the impact of residual moisture-b... by Tibebu Kassawmar (5120267)

“…The results show that only 39% of the basin is currently cultivated, although a significant cropland expansion (10%) was recorded between 1985 and 2020. …”

Data Sheet 1_Effects of continuous cropping on soil metabolomics and rhizosphere bacterial communities in Panax quinquefolius L..docx by Jian Song (4232)

“…Microbial community composition was assessed using Illumina high-throughput sequencing, and metabolite profiles were analyzed using non-targeted metabolomics (UPLC-MS/MS).</p>Results<p>Significant decreases were observed in soil pH (12.2–28.0%), cation exchange capacity (42.6–65.5%), organic matter (8.7–27.3%), total nitrogen (7.6–27.8%), and ammonium (NH₄⁺) content (16.9–56.6%) with an increasing number of continuous cropping years. …”

Table 5_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Image 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…In parallel, spectral imaging further revealed post-treatment shifts in macrophage populations, with a significant decrease in inflammatory subsets (CD14+, CD14+/Mac387+, p<0.05) and an increase in anti-inflammatory subsets (CD16+, CD16+/CD163+, CD16+/CD68+, p<0.05). …”

Image 8_Can posttreatment blood inflammatory markers predict poor survival in gynecologic cancer?: a systematic review and meta-analysis.tiff by Minyong Choi (22465405)

“…Early sampling of within one month after treatment completion (≤ median 15 days) showed prognostic significance (pooled hazard ratios 3.43–3.55; p < 0.0001), whereas late sampling demonstrated no significant associations. …”

Image 1_Comparative analysis of cranberry fruit rot fungal diversity in Massachusetts from wild, organic, and conventional ecosystems using multiplex PCR.jpg by Salisu Sulley (22059035)

“…Organic bogs exhibited a significant decline in species richness from 6 fungi in 2021 to 2 fungi in 2022. …”

DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx by Teng Qi (278739)

“…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. High GLI1 expression indicated better survival outcomes and was correlated with the age and stage of BRCA patients. …”