Data Sheet 1_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... حسب Yao Wang (102387)

"…</p>Conclusion<p>In conclusion, although SGLT2i increase the risk of EKA and GUI and GLP-1RA decrease the risk of AKI, SGLT2i are at comparable risk of MACE, HHF, MI, stroke, hypoglycemia, and fracture to GLP-1RA.…"

Table_2_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... حسب Kexin Zhang (301752)

"…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …"

Supplementary file 1_Comparison of the ruminal microbiome responses of temperate and tropically adapted beef steers to dietary supplementation with monensin.docx حسب Ross L. Thorn (22688840)

"…SCFA analysis showed a decrease in the acetate/propionate ratio (p = 0.001) across all breed types under monensin treatment. …"

Table2_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.xlsx حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Presentation 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.pptx حسب Bo Peng (273834)

"…In the US, ASIR continued to rise, ASPR decreased before 1995 and then increased, with fluctuations in ASMR and ASDR. …"

Analyses of directed phase lag index (dPLI [44]) for excitatory/inhibitory (E/I) ratios with respect to pyramidal (Pyr) and parvalbumin (PV) populations (<i>A</i>) and Pyr and soma... حسب Nobuhiko Wagatsuma (494052)

"…However, in contrast to the E/I ratio for the PV population, increasing the E/I ratio by decreasing SOM interneuron numbers tended to decrease the dPLI values from PV to Pyr populations. …"

Image2_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Table 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx حسب Joanna Palade (17712960)

"…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …"

Table 1_Promising benefits of six-month Phaeodactylum tricornutum microalgae supplementation on cognitive function and inflammation in healthy older adults with age-associated memo... حسب Emily Goodbody (21216737)

"…Similar findings were reported for participants’ perceived stress (p = -0.04; Cohen’s d = 0.4). There was a significant decrease in blood hs-CRP from 3.9mg/L to 2.1mg/L following 24-weeks of Pt extract supplementation as compared to placebo (p = 0.002; Cohen’s d = 0.8), while there was no adverse impact on safety clinical blood tests or reported side effects, with the product deemed safe and tolerable.…"

Inclusion and exclusion criteria. حسب Tong-jie Yang (20939652)

"…</p><p> Conclusion </p><p>(1) HU can effectively contribute to the evaluation of bone and soft tissue densities in the proximal femur, and reflect local stress changes. (2) In ONFH patients, bone density does not decrease in the necrotic area of the femoral head before collapse. …"

Data Sheet 1_DYRK1A roles in human neural progenitors.docx حسب Jeremie Courraud (20871932)

"…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …"

Image 2_CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target.tif حسب Chao Zeng (452370)

"…High expression of both proteins was significantly associated with lymph node metastasis in PTC patients, and a significant positive correlation was observed between CXCR7 and TAGLN2 expression levels. …"

Table 4_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx حسب Zhicong Wang (810566)

"…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …"

Data Sheet 1_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

DataSheet1_Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuri... حسب Yang Wang (5921)

"…</p>Results<p>In HN mice, C. spicatus could significantly reduce serum uric acid levels and improve renal function. …"

Image 1_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

Table 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx حسب Joanna Palade (17712960)

"…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …"

Image 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg حسب Joanna Palade (17712960)

"…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …"

Image3_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.jpeg حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Image 1_CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target.tif حسب Chao Zeng (452370)

"…High expression of both proteins was significantly associated with lymph node metastasis in PTC patients, and a significant positive correlation was observed between CXCR7 and TAGLN2 expression levels. …"