Image 1_Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling.tif حسب Yujie Shi (737203)

"…Combination treatment induced significant G0/G1 cell-cycle arrest, reduced ALDH1⁺ populations, and decreased tumorsphere formation. …"

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx حسب Jian-Tong (21583487)

"…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …"

Model inputs. حسب Natalia Serpetti (5260715)

"…The spatial/temporal model successfully simulated the overall ongoing declining dynamics of the Black Sea ecosystem as the biomasses of the majority of the functional groups had significant observed decreasing trends during the simulation period. …"

Data Sheet 2_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.xlsx حسب Farzana Gul (7119200)

"…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. We investigated the effects of intermittent and Ramadan fasting on the gut microbial composition, diversity, and short-chain fatty acid (SCFA) profile in a Pakistani population.…"

Supplementary file 1_Spatiotemporal monitoring in beidagang wetland using Landsat time-series images and Google Earth Engine during 2000–2022.docx حسب Xinyue Zhang (271120)

"…However, the existing wetland products lack the ability to capture and update the dynamic changes in time and space, with less attention to the classification based on hydrological processes and vegetation types. Therefore, we developed a Decision Tree (DT)-based classification method, incorporating water frequency (WF) and vegetation frequency (VF) calibrated with field observations, to monitor wetland dynamics using Landsat-5/7/8/9 time-series images (2000–2022) and Google Earth Engine (GEE). …"

Data Sheet 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx حسب Man Zhao (314232)

"…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …"

Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf حسب Annel P. Koomen (20406923)

"…Smoking cue–induced craving and physiological measures were assessed at baseline (T0) and 1 day after the intervention (T4), and smoking behavior was measured at T0 and 2-week (FU1) and 3-month (FU2) follow-up.</p>Results<p>Significant decreases in cue-induced craving from T0 to T4 and daily cigarette use from T0 to FU1 and FU2 were observed but not differ between the two experimental groups. …"

Data Sheet 1_Increased risk of deep vein thrombosis, pulmonary embolism, and all-cause mortality in chronic venous disorder: a large-scale retrospective cohort study.docx حسب Eva Lotta Moderegger (22389298)

"…Background<p>Chronic venous disorder (CVD), often overlooked as a significant medical burden, has recently been linked to severe health risks, especially deep vein thrombosis (DVT), and pulmonary embolism (PE). …"

DataSheet1_Apoptotic and proliferative processes in the small intestine of rats with type 2 diabetes mellitus after metformin and propionic acid treatment.PDF حسب Larysa Natrus (9397898)

"…Western blotting, RT-PCR, and scanning electron microscopy were performed.</p>Results<p>We observed profound changes in the SI of diabetic rats suggesting the disturbed intestinal homeostasis: impaired mitochondrial ultrastructure, increased cristae volume, and decreased content of proliferative marker Ki67 with almost unchanged proapoptotic caspase-3 and its p17 subunit levels. …"

Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc حسب Jianhua Li (36075)

"…The number of bacterial keystone taxa was first increased and then decreased, with Bacillota (formerly Firmicutes) being the dominant keystone phylum. …"

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …"

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …"

Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx حسب Nikola Habek (21178259)

"…Background<p>Preclinical and clinical research of insulin resistance and glucose homeostasis in metabolic disorders are essential. In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…"

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx حسب Jian-Tong (21583487)

"…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …"

Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf حسب Antonio Pannico (4890952)

"…Introduction<p>We investigated the influence of genetic material and light spectrum on plant performance of two cultivars of potato (Solanum tuberosum L.), ‘Colomba’ and ‘Libra’, grown in greenhouse, in the view of future plant cultivation in Space and terrestrial vertical farming and controlled environment agriculture under limiting light conditions.…"

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …"

Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri... حسب Stephan R. Vavricka (8994197)

"…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …"

Data Sheet 1_A novel bivariate nomogram for predicting sequela vaginal lesions after surgery in patients with HPV-associated cervical cancer.docx حسب Yueheng Liu (9228588)

"…Then we built three predictive models; multiple logistic regression was optional, with its AUC at 0.7955 in the ROC curve.…"

Data Sheet 1_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.csv حسب Farzana Gul (7119200)

"…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. We investigated the effects of intermittent and Ramadan fasting on the gut microbial composition, diversity, and short-chain fatty acid (SCFA) profile in a Pakistani population.…"

Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx حسب Naama Lax (20998004)

"…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …"