Data_Sheet_1_miR-124 Alleviates Ischemic Stroke-Induced Neuronal Death by Targeting DAPK1 in Mice.docx by Yan Shi (166398)

“…</p>Results<p>In vivo and in vitro results demonstrated that levels of miR-124 were significantly decreased following stroke, whereas changes in death-associated protein kinase 1 (DAPK1) levels exhibited the converse pattern. …”

Supplementary Material for: How the COVID-19 Pandemic Impacted Neurological Hospital Admissions in Germany - A Retrospective Analysis by figshare admin karger (2628495)

“…While overall admissions decreased, average case severity was significantly higher. …”

Table 5_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 1_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.pdf by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…However, the underlying pathophysiological mechanisms remain incompletely understood.</p>Methods<p>We administered DNase I to MRL/lpr mice, monitored signs and renal pathology, quantified gene expression levels, and conducted flow cytometry and RNA-seq analysis. …”

Table 1_Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression.xlsx by Fangmin Zhong (17415318)

“…</p>Results<p>Compared with normal samples, CML samples had significantly lower autophagy scores and more downregulated ARGs. …”

Image 1_Myo-inositol improves developmental competence and reduces oxidative stress in porcine parthenogenetic embryos.tif by Ali Jawad (1728757)

“…Myo-Ins supplementation also decreased the rate of apoptosis and the apoptotic index in the treatment groups. …”

Image 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.tif by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx by Manling Zhang (566460)

“…However, the underlying pathophysiological mechanisms remain incompletely understood.</p>Methods<p>We administered DNase I to MRL/lpr mice, monitored signs and renal pathology, quantified gene expression levels, and conducted flow cytometry and RNA-seq analysis. …”

Data Sheet 1_Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.docx by Rebecca Rothe (10292883)

“…In addition, immune cell subsets varied significantly in their differentiation and phenotypic marker expression. …”

Table 4_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Table_4_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.docx by Ling Li (38566)

“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”

Table 3_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

“…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”

Table 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Table 5_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Data Sheet 1_Clinical characteristics and outcome of very old (≥90 years) critically ill patients with need for intensive care after surgical intervention.docx by Jöran Lücke (14948623)

“…Background<p>Due to increasing life expectancy and decreasing morbidity, society is aging. Especially the group of very old patients (≥90 years) is currently increasing significantly. …”

Data Sheet 1_Parent soil type modulates biochar and mowing effects on soil microbial communities in karst region.docx by Xun Yi (2167936)

“…Highthroughput sequencing was used to assess microbial abundance, alpha diversity, and community structure.</p>Results<p>We found that the individual and combined effects of biochar and mowing on soil microbial communities differed significantly between soil types. …”

Data Sheet 1_Higher soil nitrous oxide production in landscape depressions linked to soil and hydrological legacy effects.docx by Yujia Liu (318262)

“…Depression soils exhibited 3,000- and 4,000-fold higher 16S rRNA and nosZ clade I abundances, respectively, compared to upland soils. Cu addition significantly decreased 16S rRNA abundance, eliminated AOB amoA in upland soils, and slightly reduced the tested gene abundances in depression soils. …”