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61
Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
Published 2025“…Snake venom, consisting of a complex mixture of bioactive proteins and peptides, has demonstrated significant anti-cancer effects such as cytotoxicity, angiogenesis inhibition, and apoptosis induction. …”
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62
Aspirin inhibition and recovery of cyclooxygenase activity and thromboxane biosynthesis in human megakaryocytes: a translational surrogate model
Published 2025“…These findings identify COX-1 as the principal source of TXA<sub>2</sub> in megakaryocytes and demonstrate that aspirin inhibits megakaryocyte COX-1 time- and dose-dependently, with delayed recovery likely reflecting de <i>novo </i>synthesis of COX-1 protein, thereby providing mechanistic insight into the sustained antiplatelet effect of low-dose aspirin in humans. Significance Statement In human megakaryocyte cell lines, once-daily aspirin treatment at low-concentration range time-dependently inhibits COX-1 with delayed recovery after aspirin withdrawal. …”
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…Its identification of ten factors affecting risk governance in Dubai is based on opinions of professional working in the sector. …”
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65
The multiomics analyses of cancer stem cells isolated from solid tumors can provide insight for their immunological characterization.
Published 2023“…Primary analysis of the significantly expressed miRNAs have identified target genes and their regulators involved in immune related pathways.…”
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66
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. …”
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Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review
Published 2023“…Studies reporting proteomics information and confirming SCLC and/or LCNEC through histopathological and/or cytopathological examination were included, while review articles, non-original articles, and studies based on animal samples or cell lines were excluded. …”
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69
High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…BackgroundIn the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …”
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70
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. …”
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71
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Published 2011“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
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72
Spectral domain optical coherence tomography predictors of visual outcome in diabetic cystoid macular edema after bevacizumab injection
Published 2014“…Univariate and multivariate analyses were performed comparing the optical coherence tomography findings between the two groups of eyes: the “No improvement” and the “Improvement” groups, based on at least two Snellen lines improvement after treatment. …”
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73
An Enhanced Approach for Solar PV Hosting Capacity Analysis in Distribution Networks
Published 2022“…These algorithms calculate the optimal HC based on six scenarios of annual load and DER generation profiles. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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75
The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis
Published 2020“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…<h3>Background </h3><p dir="ltr">In the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
Published 2018“…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …”
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Effect of Flexural NSM-FRP Bars on the Shear Strength of Reinforced Concrete Beams
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80
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
Published 2020“…The data were normalized and upregulated, and downregulated genes were identified based on the logFC values. Gene Ontology (GO) and pathway analysis identified the most significant pathways and genes involved in CLBC pathogenesis. …”
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