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Metal–Organic Framework-Based Drug Delivery Systems for Cancer Therapy: A Review
Published 2026“…Cancer remains one of the most significant global health challenges, with conventional treatments limited by side effects and resistance to drugs. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Comparative analysis of metaheuristic load balancing algorithms for efficient load balancing in cloud computing
Published 2023“…The primary objective of load balancing is to map workloads to use computing resources that significantly improve performance. …”
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Weather Sensitivity Of Physically Based Model Of Residential Air-Conditioners For Direct Load Control: A Case Study
Published 2020“…Hot and humid summer seasons lead to a significant proportion of the supplied power being used on air-conditioning. …”
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Weather Sensitivity Of Physically Based Model Of Residential Air-Conditioners For Direct Load Control: A Case Study
Published 2020“…Hot and humid summer seasons lead to a significant proportion of the supplied power being used on air-conditioning. …”
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LQG-Based Virtual Inertial Control of Islanded Microgrid Load Frequency Control and DoS Attack Vulnerability Analysis
Published 2023“…<p dir="ltr">The load frequency control (LFC) in modern power system like microgrid has turned out to be significantly challenging due to the high penetration of renewable energy sources (RESs) and the consequent reduction of overall system inertia. …”
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Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks
Published 2025“…This paper proposes improved cell association schemes based on the battery levels of UE and Deep Q-learning (DQL) to achieve load balancing and to decrease the power consumption of Low Battery Users (LBUs). …”
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An evolutionary approach to load balancing parallel computations
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”