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20301
Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”
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20302
Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”
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20303
Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx
Published 2025“…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …”
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20304
The result of the Negative Binomial Regression.
Published 2025“…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…”
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20305
Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…”
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20306
Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
Published 2025“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”
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20307
Analysis of connexin 43 expression in mice inoculated intravenously with EVs (green) or ICs (blue).
Published 2025“…<p>Confocal microscopy revealed decreased connexin 43 synthesis in mice injected with EVs and ICs <b>(A)</b>. …”
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20308
A fast <i>in situ</i> hybridization chain reaction method in <i>Drosophila</i> embryos and ovaries
Published 2024“…Ethylene carbonate was added to the hybridization buffer to facilitate the hybridization reaction, and a modified short hairpin DNA was used in the amplification reaction; these modifications decreased the RNA staining time from 3 days to 1 day. …”
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20309
Structure of the OHC model.
Published 2025“…<p>In this study, we employed Depthwise Separable Convolution to significantly reduce the model's parameters, decreasing complexity, thus expediting training and reducing the risk of overfitting. …”
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20310
Image 1_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”
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20311
Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”
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20312
Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”
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20313
Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”
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20314
Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”
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20315
Validation of an abortive response with elevated NF-κB activity distinct from full lytic reactivation.
Published 2024“…(D) Frequencies of <i>CD38</i><sup>+</sup> and <i>BCL2A1</i><sup>+</sup> cells presented in 3C by treatment condition at 24 h and 48 h. Asterisks denote significantly decreased frequencies of <i>CD38</i><sup>+</sup> cells and increased frequencies of <i>BCL2A1</i><sup>+</sup> cells upon 4HT and 4HT+PAA treatment versus respective control treatments (n = 3 per condition; two-tailed Welch’s t-test; **p<0.01). …”
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20316
Table_1_Major air pollution and climate policies in NYC and trends in NYC air quality 1998–2021.docx
Published 2024“…In our CCCEH cohorts, between 1998 and 2016, the annual average PM<sub>2.5</sub> and NO<sub>2</sub> concentrations also decreased significantly by 51 and 48%, respectively. …”
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20317
Supplementary file 1_Clinical application of combined anticoagulation therapy in anti-MDA5 antibody-positive associated interstitial lung disease-a retrospective study.docx
Published 2025“…Meanwhile, C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine Kinase (CK) levels decreased significantly. Also, the incidence of complications and acute exacerbation was lower in the combined group (P < 0.05). …”
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20318
In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes
Published 2025“…<b>Pt1</b> was more selective and effective in decreasing the viability of 4T1 breast cancer cells by promoting both early- and late-stage apoptosis. …”
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20319
In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes
Published 2025“…<b>Pt1</b> was more selective and effective in decreasing the viability of 4T1 breast cancer cells by promoting both early- and late-stage apoptosis. …”
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20320
DataSheet1_Diphenyl diselenide protects against diabetic kidney disease through modulating gut microbiota dysbiosis in streptozotocin-induced diabetic rats.docx
Published 2024“…</p>Results<p>The results showed DPDS and metformin improved the DKD in STZ rats, as evidenced by decreased blood glucose, BUN, urine volume, urine microalbumin, urinary β2 microglobulin, and improvement of renal pathological morphology. …”