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significant decrease » significantly increased (Expand Search)
significant main » significant gap (Expand Search), significant amount (Expand Search), significant cause (Expand Search)
main decrease » gain decreased (Expand Search), mean decrease (Expand Search), point decrease (Expand Search)
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19041
Table 2_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx
Published 2025“…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
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19042
Image 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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19043
DataSheet1_UV-B induced flavonoid accumulation and related gene expression in blue- grained wheat at different periods of time.zip
Published 2024“…</p>Discussion<p>The expression of these genes decreased after early UV-B irradiation, but increased later. …”
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19044
Data Sheet 2_Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway.doc
Published 2025“…</p>Results<p>Results indicated that Op D reduced blood glucose levels, improved glucose tolerance, enhanced insulin secretion, mitigated pancreatic atrophy, and increased PDX1 and FOXO1 expression levels. Furthermore, Op D inhibited ER stress, decreased GRP78 expression, reduced NGN3 levels, elevated PDX1, NKX6.1, and MAFA expression, and decreased oxidative stress-related products (ROS, MDA) while increasing SOD and GSH levels.…”
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19045
Table 2_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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19046
Table 1_Global burden of lower respiratory infections attributable to cytomegalovirus, 1990–2021: a systematic analysis from the MICROBE database.docx
Published 2025“…From 1990 to 2021, both ASMR and ASDR for CMV-attributable LRI decreased as SDI increased, and projections indicate a continued decline over the next 30 years.…”
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19047
Table 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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19048
Data Sheet 1_Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway.doc
Published 2025“…</p>Results<p>Results indicated that Op D reduced blood glucose levels, improved glucose tolerance, enhanced insulin secretion, mitigated pancreatic atrophy, and increased PDX1 and FOXO1 expression levels. Furthermore, Op D inhibited ER stress, decreased GRP78 expression, reduced NGN3 levels, elevated PDX1, NKX6.1, and MAFA expression, and decreased oxidative stress-related products (ROS, MDA) while increasing SOD and GSH levels.…”
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19049
Table S13 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes
Published 2025“…<p>Categories and percent frequency of significantly decreased chromatin accessibility regions</p>…”
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19050
Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx
Published 2025“…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …”
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19051
Hemostatic changes following COVID-19 vaccination: Do they promote a pro-thrombotic state?
Published 2024“…BNT162b2 group platelet counts increased significantly on day 7 (<i>p</i> = .010). …”
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19052
Data Sheet 1_Relay intercropped soybean promotes nodules development and nitrogen fixation by root exudates deposition.docx
Published 2024“…Compared with monocropping, the nodule number significantly decreased in relay strip intercropping soybean, and NTS achieved 97% at soybean five trifoliolate stage. …”
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19053
DataSheet1_Changes in serum uteroglobin level in type 2 diabetes mellitus patients.docx
Published 2024“…</p>Conclusions<p>Uteroglobin is a sensitive factor that was decreased even in prediabetes and increased upon treatment with drugs with anti-inflammatory effects. …”
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19054
Data Sheet 1_Impact of a multifaceted intervention including a smart reminder system for intraoperative antibiotic re-dosing on surgical site infections in a Chinese tertiary care...
Published 2025“…The proportion of intraoperative additional antibiotic administration also increased significantly (p = 0.003). Furthermore, the rate of SSIs decreased significantly after the intervention (p = 0.038).…”
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19055
Raw data DOI 10.3389fphar.2024.1483686.zip
Published 2024“…In terms of mechanism, JJJG significantly increased the levels of FT3 and FT4 and decreased TSH level in serum (P<0.05). …”
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19056
Image 1_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif
Published 2025“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”
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19057
Image 1_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.tif
Published 2025“…Our previous study showed that R. solanacearum significantly upregulates SlWRKY75 expression in tomato. …”
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19058
Image 2_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif
Published 2025“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”
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19059
Data Sheet 1_Real-world analysis of leuprorelin acetate microspheres-based neoadjuvant therapy for patients with high-risk prostate cancer.docx
Published 2025“…Testosterone showed a decreased tendency after neoadjuvant therapy, but without statistical significance (P=0.185). …”
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19060
Table 2_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.doc
Published 2025“…Our previous study showed that R. solanacearum significantly upregulates SlWRKY75 expression in tomato. …”