Data Sheet 4_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Data Sheet 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Table 1_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.docx by Dongli Cao (18700097)

“…An inflammatory EC subtype, exhibiting significantly increased abundance and characterized by high expression of neutrophil-recruiting factors such as Spp1 (osteopontin), CCL (C-C motif chemokine ligand), and ESAM (endothelial cell–selective adhesion molecule), suggesting active involvement in neutrophil influx and persistent inflammation. 2. …”

Data Sheet 1_Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma.docx by Ângela Marques-Magalhães (20924831)

“…We found that MLo-1508 significantly decreased RCC cell viability while inducing apoptosis in a dose-dependent manner without cytotoxicity for non-malignant cells. …”

Figure 3 from A Proteomic Signature for Human Papillomavirus–Associated Oropharyngeal Squamous Cell Carcinoma Predicts Patients at High Risk of Recurrence by Christopher C. Jackson (21027397)

“…Axes show FC > 1.5 and adjusted <i>P</i> value (adj. P Val) < 0.01. Significantly DAPeps are indicated in red (increased in R) or blue color (decreased in R). …”

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx by Shenghua Lu (20762612)

“…Regarding neurological function, the BCP combination group significantly increased the Glasgow Coma Scale score (MD = 1.86, 95% CI 1.17 to 2.56, p < 0.00001) and decreased the National Institutes of Health Stroke Scale score (MD = −2.17, 95% CI −3.35 to −0.99, p = 0.0003). …”

Table 1_Optimization of ultrasonic-assisted extraction of total flavonoids from Zanthoxylum bungeanum residue by response surface methodology and evaluation of its algicidal proper... by Jie Cheng (294193)

“…Meanwhile, treatment with Z. bungeanum residue extract at doses of 40.0 mg/L significantly decreased the Fv/Fm and PIabs values of T. obliquus by 24.36 and 88.87% at 50 h, respectively. …”

Supplementary file 2_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx by Guixin He (2547469)

“…</p>Results<p>Analysis results showed that multivariate logistic regression identified increasing age, increased absolute counts (AC) of CD4+CD38−T cells, and decreased AC of CD4+CD28−T cells as independent risk factors for CRF (P < 0.05). …”

<b>IMPACT OF MULTIVITAMINS AND PROCESSED MEAT ON AGING: A MACHINE LEARNING APPROACH</b> by Mohcene M. (20142864)

“…</p><p dir="ltr">This suggests that processed meat consumption is linked to an increased aging gap, whereas vitamin intake is associated with a decreased aging gap, reflecting a positive effect on aging. …”

SEP-363856 attenuates CUMS-induced depression-like behaviours and reverses hippocampal neuronal injuries by Mengdie Li (7432913)

“…</p> <p>The antidepressant-like effects of SEP-363856 are linked to increased hippocampal neurotrophic factors, decreased hippocampus neuronal lesions, and activation of the IGF-1Rβ/PI3K/AKT signalling pathway. …”

Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx by Thomas Pluym (22046237)

“…An invasion assay demonstrated that decay rates of unwanted microorganisms increased with decreasing organic carbon content. For example, decay rates for the introduced microorganism Pseudomonas putida in NF-, UF- treated water, and untreated tap water were respectively, −0.18 h⁻¹, −0.143 h⁻¹, and −0.089 h⁻¹, indicating enhanced biostability in membrane-treated systems.…”

Table 1_Precipitation-driven restructuring of rhizosphere microbiota enhances alpine plant adaptation.xlsx by Chao Chen (195669)

“…Actinobacteria remained consistently dominant (31.56-34.62%), while Proteobacteria abundance decreased markedly in the rhizosphere post-rainfall. …”

Supplementary file 1_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx by Guixin He (2547469)

“…</p>Results<p>Analysis results showed that multivariate logistic regression identified increasing age, increased absolute counts (AC) of CD4+CD38−T cells, and decreased AC of CD4+CD28−T cells as independent risk factors for CRF (P < 0.05). …”

Table 1_Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy.xlsx by Ziyi Li (349831)

“…Urinary TMAO was significantly decreased in both hypertensive groups, while serum TMAO remained unchanged. …”

Data Sheet 1_Plants accumulate abscisic acid after Ralstonia solanacearum infection for enhanced dehydration tolerance and plant resistance.docx by Yao Wang (102387)

“…Notably, foliar spraying 0.78 mg/L ABA could alleviate the wilting by increasing Ψ_leaf and decreasing the stomatal size, stomatal conductance (Gs), and transpiration rate (Tr). …”

Data Sheet 1_Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth.pdf by Archana Shrestha (3641959)

“…The dual miR upregulation increased the G2 phase cell population and decreased cell proliferation, motility, migration, and colony formation. …”

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”

Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”

Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx by Hua-Liang Li (20812799)

“…</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …”

Data Sheet 5_Overexpression of NK4 gene in TU212 affects migratory activity in laryngeal squamous cell carcinoma.xls by Yixuan Huo (21783825)

“…Functional experiments showed that PLV-NK4-TU212 cells exhibited a significantly reduced migration rate, decreased proliferative ability, and increased apoptosis rate. …”