Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …”

Drive‐up INR testing and phone‐based consultations service during COVID‐19 pandemic in a pharmacist‐lead anticoagulation clinic in Qatar: Monitoring, clinical, resource utilization... by Eman N. Alhmoud (14778706)

“…Patients' experience was explored through a structured survey.</p> <h3> Results</h3> <p>There was no statistically significant difference between clinic-based and phone-based anticoagulation services in mean time and number of visits within therapeutic range (<i>P</i> = .67; <i>P</i> = .06 respectively); mean number of extreme subtherapeutic and supratherapeutic INR values (<i>P</i> = .32 and <i>P</i> = .34, respectively); incidence of thromboembolic complications and warfarin related hospitalization. …”

Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. …”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”

Preparation of Mesoporous/Microporous MnCo₂O₄ and Nanocubic MnCr₂O₄ Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... by Anchu Ashok (14152020)

“…Chronoamperometric (CA) runs for 24 h shows excellent stability of MnCo₂O₄ without any significant decrease in the current or potential value in ORR and OER. …”

Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... by Amir Vahedian-Azimi (11177056)

“…Additionally, a longer LFT was found to be associated only with a higher probability of prolonged CPR (OR: 1.818, 95%CI: 1.332–3.312, <i> P</i>= 0.006). …”

An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…Consequently, choosing a system to enhance water infiltration in an agricultural terrain seems site-specific. …”
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Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Effects on in vivo ectopic bone formation were assessed by implanting hMSC mixed with hydroxyapatite-tricalcium phosphate granules subcutaneously in 8-week-old female nude mice, and the amount of bone formed was assessed using quantitative histology. Results. BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”

The effects of Salvia Officinalis leave on hyperlipidemia, glycemia, ulcer, inflammation, and bactericidal activity. (c2006) by Alayan, Iman

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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia by Taher, Ali

“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Effect of acute and chronic grapefruit, orange and pineaple juice consumption upon blood lipoprotein synthesis and metabolism in the rat. (c2004) by Abou-Khalil, Jamil

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Formation of Trihalomethanes during Seawater Chlorination by Ahmed Abdel-Wahab (1748986)

“…Rapid decrease of UV absorbance at 254 nm was also observed during seawater chlorination which is indicative of natural organic matter degradation into small organic molecules including THMs and other by-products. …”

G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome by Francesco Casciello (18557613)

“…Moreover, inhibition of G9a histone methyltransferase activity in mice using a specific small molecule inhibitor significantly reduced growth and colonisation of breast cancer cells in the lung. …”

Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles by Muneer M. Ba-Abbad (14151660)

“…Overall, the results of this study showed that embedding a small amount of Co²⁺ ions doped ZnO NPs with PSf has significant potential to be applied in industrial-scale membrane applications.…”

Past, present and future global mangrove primary productivity by Mark Chatting (5728340)

“…The models showed a slight global decrease in NPP of approximately 1.4 %, from 239.2 ± 87.6 Tg yr⁻¹ (1980–1990) to 235.9 ± 81.9 Tg yr−1 (2085–2094). …”

Dysregulated FOXM1 signaling in the regulation of cancer stem cells by Gulab Sher (12984698)

“…<p>Since the introduction of the cancer stem cell (CSC) paradigm, significant advances have been made in understanding the functional and biological plasticity of these elusive components in malignancies. …”

Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics by Fakher Hamdi (21225134)

“…Thermal efficiency shows a reverse behaviour, with a small negative impact of ethanol addition. …”

A photoactivatable Ru (II) complex bearing 2,9-diphenyl-1,10-phenanthroline by Mansour, Najwa

“…The photoproduct of complex 1 showed similar effects on key apoptotic protein expression confirming that it is behind the observed cell death. …”
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Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration by Zaatiti, Hayat

“…Of note, L1-CAM, HMGA1 and FABP5 KD concomitantly downregulated MYCN protein expression and MYCN KD concomitantly downregulated L1-CAM, HMGA1 and FABP5 protein expression, while survivin protein expression was significantly downregulated by MYCN, HMGA1 and FABP5 KD. …”
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