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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…It requires proper management to decrease mortality and morbidity. Clinical scoring systems for diagnosing AA aimed to decrease the use of radiological scans and the rate of negative appendectomies (NA). …”
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Efficient Integration of Direct Air Capture With HVAC System
Published 2025“…<p dir="ltr">Direct Air Capture (DAC) is a pivotal negative emissions technology uniquely capable of capturing CO<sub>2</sub> from unaddressed sources such as transportation, construction, and agriculture. …”
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Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis
Published 2017“…The mutation and neoantigen load progressively decreased from ICR4 to ICR1 but could not fully explain immune phenotypic differences. …”
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Exploring urban growth–climate change–flood risk nexus in fast growing cities
Published 2022“…Pearson correlation coefficient between flood risk and urban growth was strong (0.83) and significant at p < 0.05. Flood risk has a strong significant positive (negative) correlation with air temperature (wind speed) and a moderate positive (negative) correlation with precipitation (potential evapotranspiration). …”
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Psychological inoculation against problematic social media use among adolescents: An experimental study
Published 2025“…The passive inoculation group showed a significant decrease in deception only. No changes were observed in the control group. …”
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
Published 2021“…A mild form of TBI was induced in 11-week old male Sprague Dawley rats by weight drop. Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …”
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Khalasa date palm leaf fiber as a potential reinforcement for polymeric composite materials
Published 2021“…CE applications can be a viable option for the sustainable production of polymeric composite materials by decreasing the cost and improving product lifetimes and mechanical performance. …”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Our analysis reveals that the vocabulary has changed significantly and multiple spellings exist for several words. …”
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Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
Published 2024“…However, there was no significant impact on cardiovascular function and mitochondrial bioenergetics. …”
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Antibacterial Properties of Polysulfone Membranes Blended with Arabic Gum
Published 2019“…These changes were due to the amphiphilic properties of AG macromolecules that contained negatively charged hydrophilic residues. A pronounced decrease in bacterial attachment was seen in the field emission scanning electron microscopy (FESEM) images for PS/AG membrane samples compared to both commercial (Microdyn-Nadir) and bare PS (without AG) membranes. …”
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
Published 2023“…Smoking was significantly more common among respondents who were older than 18 years old, married, held master's and PhD degrees, and working in non‐health‐related fields (<i>p</i> < 0.0001). …”
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Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…Thermal efficiency shows a reverse behaviour, with a small negative impact of ethanol addition. Biodiesel addition significantly increases carbon monoxide (CO) emissions, reaching an average of 190% across all speeds. …”
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Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. …”
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
Published 2023“…We found a significant decrease in the intake of vegetables, increases in the intake of soft drinks, fried food, fast food, and sweets, and a reduction in physical activity during schools’ closure compared to before. …”
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Investigating the Impact of Salinity Variations on Aerobic Granules and Activated Sludge Flocs: Emphasis on Performance Monitoring and Identification of Influential Salinity Compon...
Published 2022“…Ionic strength affected the morphology the most, where ionic strength disrupted the production of EPS components leading to increased negative sludge surface charge, poorer sludge adhesion and eventually significant reduction in sludge settling abilities. …”