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changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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7121
Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy
Published 2025“…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …”
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7122
Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg
Published 2025“…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …”
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7123
Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis
Published 2025“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”
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7124
Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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7125
Table 2_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.xlsx
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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7126
Table 1_Effect of membrane rigidification on the BrAFP1 expression and cold-tolerance in Brassica rapa.docx
Published 2025“…The expression levels of cold-responsive genes, including cyclic nucleotide-gated channel 1 (CNGC1), open stomata 1 (OST1), and inducer of CBF expression 1 (ICE1), as well as membrane fluidity-related genes, such as acyl-lipid desaturase 2 (ADS2), fatty acid desaturase 2 (FAD2), and sensitive to freezing 2 (SFR2), were significantly increased following DMSO pretreatment, while BA treatment significantly inhibited the expression of these genes. …”
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7127
Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf
Published 2024“…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …”
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7128
Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”
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7129
Table 1_Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometriti...
Published 2025“…After PRP treatment, the proportions of endometrial CD8<sup>+</sup> T cells, CD56<sup>+</sup> NK cells, Foxp3<sup>+</sup> Treg cells, and T-bet<sup>+</sup> Th1 cells were significantly decreased in patients with persistent CE. …”
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7130
Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”
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7131
Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Sperm proteins were analyzed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis page (SDS-PAGE) and liquid chromatography-mass spectrometry (LC-MS), and differentially expressed proteins (DEPs) were identified based on significance test results and fold change thresholds. …”
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7132
Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx
Published 2025“…In FaDu HSCC cells, siRNA-mediated HDGF knockdown significantly attenuated proliferation, migration, and invasion. …”
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7133
Table 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.xlsx
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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7134
Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif
Published 2025“…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”
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7135
Image 3_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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7136
Image 2_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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7137
Supplementary file 1_The bridge between anxiety and insomnia symptoms among Chinese adults before and after SARS-CoV-2 vaccination: a network analysis.doc
Published 2025“…</p>Conclusions<p>The proportion of participants experiencing anxiety and insomnia decreased significantly after SARS-CoV-2 vaccination. …”
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7138
The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study
Published 2025“…</p> <p>After eight weeks of metformin intervention, prolactin levels significantly decreased from 39.7 ± 20.0 ng/mL at baseline to 35.7 ± 15.7 ng/mL (<i>p</i> = 0.005) with a moderate effect size (Cohen’s <i>d</i> = 0.545). …”
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7139
Data Sheet 1_Splenic volume as a predictor of survival in cancer patients treated with immune checkpoint inhibitors.docx
Published 2025“…Additionally, HCC patients who experienced an increase in spleen volume during ICI therapy exhibited significantly poorer OS (HR: 2.27, 95% CI: 1.17–4.41, p = 0.016) and PFS (HR: 2.40, 95% CI: 1.30–4.41, p = 0.005) than those whose spleen volume decreased. …”
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7140
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein
Published 2025“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”