First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Characterization of systolic pulmonary arterial pressure (sPAP) of WT BMP9 in rats. by Tobias G. Schips (21799838)

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Pharmacological characterization of WT BMP9 and A347E variant <i>in vitro</i> and <i>in vivo.</i> by Tobias G. Schips (21799838)

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Summary of cell-based assay EC50 results for WT BMP9 and A347E variant. by Tobias G. Schips (21799838)

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Evaluation of chronic <i>in vivo</i> efficacy in 21 days rat MCT model in prevention mode. by Tobias G. Schips (21799838)

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Hemodynamic effects of WT BMP9 in rats. by Tobias G. Schips (21799838)

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Evaluation of chronic <i>in vivo</i> efficacy in 21 days rat MCT model in prevention mode. by Tobias G. Schips (21799838)

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<i>In vivo</i> PK evaluation of WT BMP9 in naïve SD rats. by Tobias G. Schips (21799838)

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Pharmacological characterization of WT BMP9 and A347E variant <i>in vitro</i> and <i>in vivo.</i> by Tobias G. Schips (21799838)

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Characterization of safety pharmacology of WT BMP9 in rats. by Tobias G. Schips (21799838)

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Table 1_Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large... by Changlan Li (704841)

“…The optimal cut-off for predicting deterioration was 5.54 mm for affected-side ONSD (sensitivity 81.3%, specificity 78.9%, AUC = 0.814) versus 5.57 mm for the unaffected-side (68.8, 78.9%, AUC = 0.757), with no significant AUC difference between sides. …”

Box plots to show various parameters of the rectal waves generated in AB larvae at 7 dpf that were fed a standard diet (SD). by Jessica C. M. Hui (20370522)

Box plots to show various parameters of GI motility in the anterior, mid, and posterior intestine of ED, HFD and SDG larvae compared with the SD controls, at 7 dpf. by Jessica C. M. Hui (20370522)

Box plots to show various parameters of the rectal waves ED, HFD and SDG larvae compared with the SD controls, at 7 dpf. by Jessica C. M. Hui (20370522)

Box plots to show various parameters of GI motility in the anterior, mid, and posterior intestine of ED, HFD and SDG larvae compared with the SD controls, at 7 dpf. by Jessica C. M. Hui (20370522)

Box plots to show various parameters of GI motility determined from AB larvae at 7 dpf that were fed a standard diet (SD). by Jessica C. M. Hui (20370522)