Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... by Yuanhang Rong (19207540)

“…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…”

Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... by Lei Qian (292302)

“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”

Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx by Christoph Riegler (3554054)

“…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p_trend<0.01). …”

Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx by Chen-xiao Liu (22750118)

“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”

Cued-attention is mediated by a cholinergic HDB to SAC circuit. by Rahul Garg (3064578)

“…Inset denotes glomeruli with significant changes with SAC inhibition. Yellow: increased, dark grey: decreased, light grey: unchanged. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen... by Zeng Li (688702)

“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”

Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus. by Md Rezaul Islam (19649494)

“…Color represents statistical significance after multiple testing adjustments. <b>E)</b> Signed bar plot displaying significant co-expression changes of the identified 7 gene modules in hippocampal excitatory neurons in stimulation vs ambient TsD65n mice. …”

S1 File - by Zsófia Tróznai (19923854)

“…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …”

PTEN KD induces EMT in epithelial CRC cells. by Ahmed H. Ghobashi (12705573)

“…All significant comparisons are shown. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.…”

Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen... by Zeng Li (688702)

“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”

Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen... by Zeng Li (688702)

“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”

Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen... by Zeng Li (688702)

“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”

Flowchart of the selection program. by Zsófia Tróznai (19923854)

“…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …”

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... by Deliang Kong (382201)

“…</p>Results<p>From 2016 to 2022, the incidence rate of PTB in southwest China showed a decreasing trend (AAPC = -10.22, 95% CI: −11.49% ~ −8.94%), while the incidence rate of PTB-DM increased rapidly (AAPC = 14.25, 95% CI: 11.35% ~17.23%). …”

Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX by Ji Zeng (4336561)

“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”

Supporting data for "DECODING THE NEUROIMMUNE AXIS OF HEAD AND NECK CANCER TO ENHANCE IMMUNOTHERAPEUTIC OUTCOMES" by Ravi Kishan (11263155)

“…Genetic ablation of PTHLH resulted in dysregulation of neurotrophic signaling pathways essential for intra-tumoral innervation, significant reduction in tumor burden, and enhanced antitumor immunity —evidenced by increased CD8+ and CD4+ T cell infiltration, as well as decreased immunosuppressive markers. …”

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. by Andrew B. Harvey (21587431)

“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”

Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se... by Patrick Schreier (19829972)

“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”

Image 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif by Bin He (75597)

“…These subtypes exhibited significantly different distributions between AF and SR. …”