Table 1_Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban commun... حسب Zhiyuan Wang (535663)

"…Neuropsychological tests, lipid/metabolic markers (n = 326), and resting-state fMRI (rs-fMRI) data (n = 216) were collected. Multivariable linear regression was used to assess associations between rs440446 and cognitive performance, lipids, and metabolic indicators. …"

Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX حسب Shaoqun Huang (19810725)

"…Weighted multivariate linear models, restricted cubic spline (RCS), and subgroup analysis were subsequently carried out to evaluate the influence of PHDI on biological aging.…"

Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip حسب Xueshan Chen (17477633)

"…Notably, highly expressed proteins in horse milk were closely linked to immune signaling pathways, functioning as immune modulators. …"

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... حسب Jingshuang Song (11340138)

"…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …"

DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

"…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …"

DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

"…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …"

Multi-Omics Insights into Microbiome and Metabolite Signatures as Potential Biomarkers for Feline Hypertrophic Cardiomyopathy حسب Yuhong Wu (21545486)

"…Compared to healthy cats, those with HCM exhibited significant gut microbiota dysbiosis, including decreased abundances of <i>Campilobacterota</i>, <i>unclassified_k_norank_d_Bacteria</i>, <i>Blautia</i>, <i>Helicobacter</i>, and <i>Ruminococcus_torques_group</i>, while <i>Romboutsia</i> and <i>Lactococcus</i> were enriched in the HCM group. …"

Image 1_Bright light exposure reduces negative affect and modulates EEG activity in sleep-deprived and well-rested adolescents.tif حسب Jana Kopřivová (14754945)

"…</p>Results<p>Bright light significantly reduced negative affect and improved Digit Span Forward task performance. …"

Data Sheet 1_Microbiome-metabolome dysbiosis of bronchoalveolar lavage fluid of lung cancer patients.docx حسب Jing Wang (6206297)

"…Metabolites increased in lung cancer were Citric acid, N-Acetylneuraminic acid, Oxoglutaric acid, and Neopterin, whereas L-Tryptophan, Uridine, 3-Hydroxybutyric acid decreased. The KEGG pathways suggest a significant link between microbial presence and both tumorigenesis and progression.…"

Image 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.pdf حسب Liping Shi (734514)

"…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …"

Table 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.csv حسب Liping Shi (734514)

"…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …"

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…"

Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... حسب Menekse Oeztuerk (20756606)

"…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …"

Image 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... حسب Menekse Oeztuerk (20756606)

"…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …"

Image_1_Barriers of the CNS transfer rate dynamics in patients with vascular cognitive impairment and dementia.TIFF حسب Saeid Taheri (339331)

"…</p>Results<p>Longitudinal BBB measurements revealed variable dynamic behavior: after two years, the BBB K_trans increased in 55% of patients and decreased in the remaining 45% unpredictably. We did not find a significant linear model of BBB K_trans versus age for VCID. …"