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281
A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle
Published 2022“…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …”
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282
The impact of different acidic conditions and food substrates on <i>Listeria </i><i>monocytogenes</i> biofilms development and removal using nanoencapsulated carvacrol
Published 2024“…However, at pH 5.5 and 6.5, increased biofilm levels were observed in both the culture media and food substrates, with the WT strain showing significantly higher biofilm formation (3.04–6.05 log CFU cm<sup>−2</sup>) than the mutant strains (2.30–5.48 log CFU cm<sup>−2</sup>). …”
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283
Comparative outcome analysis of home-initiated non-medical interventions among toddlers with orally ingested substances
Published 2015“…In regression: intervention significantly increased length of stay (t = 0.213, adj. …”
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284
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …”
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285
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…Notable COX-2 inhibitory activities (IC<sub>50</sub> = 0.065–0.24 μM) were observed relative to celecoxib (IC<sub>50</sub> = 0.049 μM). …”
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286
Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
Published 2020“…At high heating rates, a similar behavior but not that significant was observed due to the accelerated gelation in the system. …”
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287
The clinical characteristics and outcomes of patients with pulmonary hypertension in association with hyperthyroid state: A systematic review
Published 2022“…<h3>Background</h3><p dir="ltr">Pulmonary hypertension (PHTN) may occur in thyroid disorders, especially in hypothyroidism. However, there is increasing evidence of PHTN in hyperthyroidism (HTH). …”
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288
Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
Published 2024“…Oncoviruses like the Human Papilloma Virus (HPV) and the Epstein Barr Virus (EBV) are highly potent inducers of oncogenic transformation leading to tumor development. …”
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289
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…In both cell-free and cellular models of α-synuclein aggregation, after administration of DHM and Sal B, we observed significant inhibition of α-synuclein accumulation and aggregation. …”
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290
Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
Published 2019“…The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …”
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291
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas...
Published 2021“…Although global age-standardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: –1·21% [–1·26 to –1·16]), similar progress was not observed for chewing tobacco (0·46% [0·13 to 0·79]). …”
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292
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). Notably, built-up areas and desert lands consistently recorded the highest mean LST in both seasons in all observed years. …”
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293
Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…Kinetic studies showed superior correlation with the pseudo-second-order model (R<sup>2</sup> > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …”
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294
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
Published 2022“…The time required to develop bridging and subsequent clogging of the pore space that lead to permeability reduction decreases as the flow velocity increases. The size of the fine particles has a significant impact on permeability reduction where the reduction in permeability increases as the size of particles increases. …”
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295
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …”
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296
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). Notably, built-up areas and desert lands consistently recorded the highest mean LST in both seasons in all observed years. …”
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297
Estimation of power grid topology parameters through pilot signals
Published 2016“…The distribution grid has been the source of an increased amount of electricity production in recent years. …”
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298
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Published 2020“…Significantly lower NP test scores was observed in HIC than those of HUC. …”
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299
Protein and pH-dependent Binding of Nascent Pectin and Glucuronarabinoxylan to Xylogucan in Pea
Published 2000“…The observed binding may be of considerable significance in the process of cell-wall assembly and in the control of cell extension.…”
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300
Design, Implementation, and Performance Analysis of Actively
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