A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems حسب Shazia Bibi (16500318)

"…The seed radicle lengths at 2 mg mL−1 were significantly reduced for both plant species. The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …"

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Shuja Mohd Reagu (12051406)

"…</p><h3>Conclusions</h3><p dir="ltr">The rates of Obsessive–compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. The obsessive–compulsive symptoms and the intent to not breastfeed were significantly associated with fear of infection to the new-born. …"

A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation حسب AlSawaftah, Nour Majdi

"…Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). …"
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Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus حسب Hazrat Bilal (7367477)

"…Results show a substantial depletion in the groundwater thickness (0.24 ± 0.20 cm/year) during the period of observation (2002–2020). Long-term temperature data indicates that the annual mean temperature increased significantly by 1.02 °C between 1987 and 2016, while total rainfall exhibited a slight decreasing trend. …"

Effect of sintering additives on the properties of alumina toughened zirconia (ATZ) حسب M. K. G. Abbas (18021646)

"…In general, all ATZ samples exhibited a similar trend, as the results showed that the relative density and mechanical properties increased with increasing sintering temperature regardless of the addition of dopants. …"

Intratumoral FoxP3⁺Helios⁺ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer حسب Azharuddin Sajid Syed Khaja (19720114)

"…Levels of CD4⁺FoxP3⁺Helios⁺ Tregs were significantly increased in the TME. Furthermore, we observed increased levels of PD-1/CTLA-4 and PD-1/CD39 co-expressing cells within FoxP3⁺Helios⁺ and FoxP3⁺Helios⁻ Treg subsets, indicative of their potent immunosuppressive potential. …"

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care حسب Ahmad Kloub (16855149)

"…</p><h3>Methods</h3><p dir="ltr">This observational study compared injured patients admitted one year before (pre-P) and after (post-P) implementing a new VTEp protocol. …"

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department حسب Atilla Temel (17788481)

"…Thorax ultrasonography is a useful technique with high specificity in diagnosing pneumothorax, but its sensitivity decreases significantly when the size is below 1 cm.…"

One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes حسب Goran Petrovski (129836)

"…</p> <h2>Methods</h2> <p>This was a 1-year observational study, as a continuation of the previous 3 months prospective study of pediatric patients with T1D conducted at Sidra Medicine in Qatar. …"

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways حسب Khaled W. Sadek (14153196)

"…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …"

Ultrasonically Triggered Release of Folic Acid-Conjugated Liposomes for Breast Cancer Therapy Within Microfluidic Devices حسب AlHazaimeh, Taima Khair Alla

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