Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. Western blotting results revealed an upregulation in Bax:Bcl‑2 ratio, confirming the pro‑apoptotic effect of kefir, and an increase in p53 independent‑p21 expression upon kefir treatment. …"
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Deep learning-based beat-to-beat arterial blood pressure estimation using distant radar signals حسب Farhana Ahmed Chowdhury (22564808)

"…We introduce MultiResLinkNet, a segmentation model based on a one-dimensional convolutional neural network (1D CNN), specifically designed to synthesize arterial blood pressure (ABP) directly from raw radar waveforms. …"

Y-Chromosome and mtDNA Genetics Reveal Significant Contrasts in Affinities of Modern Middle Eastern Populations with European and African Populations حسب Khazen, Georges

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform حسب Rafah Mackeh (14151225)

"…This case demonstrates the value of reanalyzing genetic data based on the clinical phenotype and highlights the significance of functional studies in determining the pathogenicity of genetic variants.…"

Hydrogen bonding: a mechanism for tuning electronic and optical properties of hybrid organic–inorganic frameworks حسب Fedwa El-Mellouhi (2011099)

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…Our findings support our hypothesis that T1 exerts its anti-cancer effects by inhibiting BC invasion and inducing apoptosis mediated, at least, <i>via</i> the p53/Bax/Bcl2 pathway. …"

Manara – Qatar Research Repository: One year after the launch حسب Marcin Werla (13761781)

"…</p> <p>The repository is open to all Qatar-based researchers, who can individually register and upload their content. …"

Impacts of climate change on the global spread and habitat suitability of <i>Coxiella burnetii</i>: Future projections and public health implications حسب Abdallah Falah Mohammad Aldwekat (22457821)

"…<h3>Introduction</h3><p dir="ltr"><i><u>Coxiella burnetii</u></i><i><u>,</u></i> an intracellular zoonotic bacterium, affectsing various livestock and <u>wildlife</u> species and poses significant risks to human health. …"

Ultraliser: a framework for creating multiscale, high-fidelity and geometrically realistic 3D models for <i>in silico</i> neuroscience حسب Marwan Abdellah (4435360)

"…Creating realistic structural models from existing ones is challenging, particularly when needed for detailed subcellular simulations. …"

Wearable wrist to finger photoplethysmogram translation through restoration using super operational neural networks based 1D-CycleGAN for enhancing cardiovascular monitoring حسب Sakib Mahmud (15302404)

"…In the first phase, corrupted wPPG waveforms are blindly restored using a 1D-CycleGAN-based restoration framework. Subsequently, in the second phase, the restored wPPG waveforms are translated into clean finger PPG (fPPG) signals through a 1D-CycleGAN-based signal-to-signal translation or synthesis framework. …"

One Dimensional Seismic Site Response Analysis of United Arab Emirates حسب Eltayeb, Ahmed Mohamed Zaroug

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Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry حسب Samah Mechmechani (12988420)

"…<p dir="ltr">The rise of antibiotic-resistant <i>Salmonella</i> in poultry poses a significant public health challenge. …"

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"

ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer حسب El Mais, Nour

"…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …"
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