Data Sheet 5_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.pdf by Paolo Romania (399007)

“…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …”

Data Sheet 1_Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona.docx by Miquel Porta (199379)

“…</p>Results<p>Higher concentrations in 2016–17 of IL-8 and TNF-α significantly decreased the risk of SARS-CoV-2 seropositivity in 2020–21, whereas higher concentrations of MIP-1α were a risk factor for seropositivity. …”

Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx by Yewen Sun (8334138)

“…Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …”

Image 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …”

Pan-cancer analysis reveals PRRT4 is a potential prognostic factor of AML by Wenqiong Xiang (17738962)

“…After PRRT4 knockdown, the proliferation ability of THP1 cells was significantly enhanced, and the apoptosis ratio was significantly decreased.…”

Image 2_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Table 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.xlsx by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.jpeg by Hana Kahleova (618836)

“…</p>Conclusion<p>These findings suggest that, compared with the Mediterranean diet, dietary acid load decreased significantly on the low-fat vegan diet and was associated with weight loss. …”

Table 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.docx by Hana Kahleova (618836)

“…</p>Conclusion<p>These findings suggest that, compared with the Mediterranean diet, dietary acid load decreased significantly on the low-fat vegan diet and was associated with weight loss. …”

Image 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Data Sheet 1_Prophylactic administration of lecithinized superoxide dismutase for a murine model of oxaliplatin-induced myelosuppression.pdf by Mikako Shimoda (9519493)

“…</p>Results<p>Oxaliplatin administration decreased the white blood cell, platelet, and red blood cell counts and hemoglobin levels in the whole blood of mice. …”

Image 4_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 5_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tif by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Data Sheet 1_Characterization of peripheral immune cells in kidney transplantation recipients under different immunosuppressive treatments.docx by Yunze Tai (21522872)

“…The use of mTOR inhibitors in KTRs induced changes in the distribution of activated and naïve-memory T cell subsets and decreased proinflammatory cytokines.</p>Discussion<p>In KTRs, G-MDSCs and M-MDSCs accumulated while functionally activated, naïve-memory T cell populations and HLA-DR⁺ monocytes markedly decreased one year after transplantation. …”

Image 3_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Data Sheet 1_Multimodal MRI reveals distinct hippocampal subregional alterations in de novo Parkinson’s disease across the cognitive spectrum.docx by Chenxi Pan (10211363)

“…</p>Results<p>Compared to the PD-NC, the PD-SCD group revealed a significantly decreased FC between the left middle hippocampus (HIPm) and right postcentral gyrus (PoCG. …”

Data Sheet 1_Assessing the efficacy and safety of pentoxifylline in preventing chemotherapy-induced peripheral neuropathy and mucositis in breast cancer patients.pdf by Samar A. Dewidar (22425457)

“…</p>Conclusion<p>The co-administration of PTX with AC/T chemotherapy in breast cancer patients significantly decreases the incidence and postpones the onset of grade 2 or higher peripheral neuropathy and the incidence of mucositis without causing additional risks for the patients.…”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…In addition, ribosome binding decreased when Ser/Thr 847 and 852–854 are substituted by a non-phosphorylatable residue, consistent with decreased protein stability, and reduced number of associated factors. …”

Supplementary file 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif by Chao Li (145513)

“…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …”

Table 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.docx by Chao Li (145513)

“…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …”