Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”

Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”

Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

“…Moreover, the levels of diamine oxidase (DAO), D-Lactate, secretory immunoglobulin A (sIgA), interleukin 6 (IL-6), IL-10, and tumor necrosis factor-α (TNF-α) were detected using enzyme-linked immunosorbent assay (ELISA) kits. The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx by Min Luo (258201)

“…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …”

Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

“…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”

<i>MMP-1</i> OE restores <i>5HT</i>_<i>2A</i><i>R</i>-deficient experience-dependent pruning. by Vanessa Kay Miller (19775496)

“…Individual data points are shown with mean ± SEM. Significance: <i>p</i> < 0.0001 (****) and <i>p</i> > 0.05 (ns). …”

Image 5_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Image 3_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Image 2_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Image 4_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Table 1_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.docx by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Image 6_Age- and sex-specific reference intervals for trace elements in infants and children: a multi-center study in Lincang, China.jpg by Junqiang Li (491954)

“…</p>Results<p>After the appropriate segmentation points are determined, the refineR algorithm is applied to calculate RIs. …”

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Image 1_Ketogenic diet–induced changes in methylation status and neuropeptide signaling: relationships between S-adenosylmethionine (AdoMet), orexin-A, and metabolic health.pdf by Laura Mosca (704904)

“…Circulating AdoMet (−75.7%) and Orexin-A (−7.2%) levels also decreased significantly. AdoMet levels positively correlated with body weight, BMI, visceral adipose tissue, total cholesterol, fasting glycemia, triglycerides, HbA1c, and notably Orexin-A (R² = 0.3848, p < 0.0001).…”

Image 2_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome by Yokoyama T. (4606381)

“…Linear regression analysis showed that renal function progressively decreases with age in patients with BLOC-3 or BLOC-2 disorders, but the rate of decline was more rapid in patients with BLOC-3 disorders compared to patients with BLOC-2 disorders. …”

Data Sheet 1_Association between life’s crucial 9 and severe abdominal aortic calcification in U.S. Adults: the mediating role of the systemic inflammatory response index.docx by Kaifeng Tang (5993231)

“…</p>Results<p>In fully adjusted models, an increase of 10 points in LC9 scores was associated with a 26% reduction in the prevalence of SAAC, achieving statistical significance (P < 0.001). …”

Table 1_Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia.docx by Tiantian Yu (5167427)

“…Lactobacillus iners was both negative to nadB and kynU genes, the predicted abundance of which was significantly higher in the CC group. The linear regression model showed that the combination of the vaginal microbiota and vaginal metabolites has good diagnostic performance for cervical cancer.…”