Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…Overall, these findings provide evidence that arginine deprivation induced by [HuArgI(Co)-PEG5000] leads to increased ROS production, lipid peroxidation, and dysregulation of iron metabolism and antioxidant pathways, all of which are hallmarks for the occurrence of ferroptosis in AML cells following arginine deprivation. …”
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Renin–angiotensin-system gene polymorphisms and depression by Saab, Yolande B.

“…None of the other common RAS-associated polymorphisms were significantly associated. The results support the hypothesis that increased RAS activity may increase relative risk of depression in that the angiotensin receptor type 1 (A1166C) CC genotype is associated with increased responsiveness to angiotensin II.…”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Results rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly associated with an increased risk of CAD with respective odds ratios of 1.53703, 1.67710, and 1.35520; the genetic variant rs9579646 (ALOX5AP) is significantly associated with a decreased risk of CAD (OR 0.76163). …”
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The role of patient positioning in surgical fixation of the calcaneus fractures using the lateral extensile approach by Hammam Kayali (14146797)

“…There was no significant difference between the two groups regarding the reoperation rate (<i>p</i> 0.947), infection (p 0.659, operative time (<i>p</i> 0.688), anesthesia time (<i>p</i> 0.522) and wound complications (<i>p</i> 0.773).…”

Impact of COVID‑19 pandemic restrictions and subsequent relaxation on the prevalence of respiratory virus hospitalizations in children by Ahmed Abushahin (17337703)

“…RSV infection rate dropped significantly during the COVID-19 season to 10.4% and then increased again during the post-COVID-19 season to 29.1% (<i>P</i> < 0.001). …”

Association Between Hypothyroidism and Hepatocellular Carcinoma: A Case-Control Study in the United States by Hassan, Manal M.

“…A history of hyperthyroidism was not significantly related to HCC (OR = 1.7; CI = 0.6-5.1). …”
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Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity by Mohamed A. Elrayess (7956179)

“…Functional enrichment analysis revealed triacylglycerols as the pathway exhibiting the most significant changes in severe COVID-19 in diabetic patients (FDR = 7.1 × 10⁻²⁷). …”

Transhepatic Ipsilateral Right Portal Vein Embolization Extended to Segment IV by Madoff, David

“…Differences in FLR volume (P = .0011), FLR/TELV ratio (P = .027), and resection rates (P = .02) were statistically significant. Seventy-one percent of patients underwent extended right hepatectomy (86% after receiving tris-acryl microspheres, 57% after receiving PVA). …”
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Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar by Dalal Al‐Sharshani (19479814)

“…<h3>Background</h3><p dir="ltr">Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD).…”

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

“…Of the four different precursors tested {Ru-I: [Ru(II)(1,10-phenanthroline)2Cl2]; Ru-II: [Ru(II)(4,7-diphenyl-1,10-phenanthroline)2Cl2]; Ru-III: [Ru(II)(4,7-diphenyl-1,10-phenanthroline-disulfonate)2Na2]2+ and Ru-IV: [Ru(II)(2,2'-bipyridine)2Cl2]}, significant activity on seven out of nine cell lines, was detected only with Ru-II (IC50 values in the low μM range). …”
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Comparison of in-hospital and out-of-hospital cardiac arrest of trauma patients in Qatar by Furqan B. Irfan (13359828)

“…IHCAT patients had significantly higher hypovolemia (OR 1.66, 95% CI 1.18–2.35, <i>p</i>=0.004), higher mean Glasgow Coma Scale (GCS) score (OR 1.4, 95% CI 1.3–1.6, <i>p</i><0.00), and a greater proportion of initial shockable rhythm (OR 3.51, 95% CI 1.6–7.7, <i>p</i>=0.002) and cardiac re-arrest (OR 6.0, 95% CI 3.3–10.8, <i>p</i>=<0.00) compared to OHTCA patients. …”

Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…Temperature affects significantly the rheological behavior of neat water Wyoming Na-bentonite dispersions. …”
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Evaluating the necessity of colonoscopy in patients under 40 with rectal bleeding: insights from a large-scale retrospective analysis by Ibrahim M. Obeidat (22224904)

“…A family history of CRC/AAP was significantly associated with increased CRC risk (adjusted OR 6.35, 95% CI 2.24–18.02, <i>p</i>= 0.001) in explorative logistic regression analysis.…”

A systematic review and meta-analysis on the impact of early vs. delayed pharmacological thromboprophylaxis in patients with traumatic brain injury by Muhammad Hamza Shuja (19748620)

“…<h3>Background </h3><p dir="ltr">Traumatic brain injury (TBI) poses significant health challenges, often leading to complications such as venous thromboembolism (VTE) and increased mortality rates. …”

Mammary adipose dysfunction in the dual epidemic of obesity and breast cancer by Elvina Jeyakumar (22997311)

“…<p dir="ltr">Breast cancer (BC) is one of the leading causes of death among women, with obesity being a significant factor. …”

Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis by Ali Ait Hssain (9538617)

“…Infected patients had lower ECMO survival and overall survival rates compared to non-infected patients, with risk ratio values of 0.84 (95% CI 0.74–0.96, <i>P</i> = 0.01) and 0.80 (95% CI 0.71–0.90, <i>P</i> < 0.001), respectively.…”

Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese by Abdelkrim Khadir (437074)

“…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …”

The downsides of information systems security policy compliance efforts by Balozian, Puzant

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Polarimetric SAR Speckle Reduction by Hybrid Iterative Filtering by Yahia, Mohamed

“…An expression that takes into account the following important numerical considerations is proposed. 1) The variability of the pixel is measured by coefficient variation (CV) rather than the variance. 2) The statistics are computed using non-local neighborhood instead of local square one. 3) A new normalizing function (i. e. hyperbolic tangent) is implemented. 4) The dynamic of range of b k is increased by multiplying the CVs of the filtered and the originals images. …”
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Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis by Allgayer, Heike

“…RESULTS By CART analysis, Src activity in tumors elevated more than twofold over normal mucosa was significant. Increased Src activity significantly correlated with Dukes stage, pT and pN classification, and increased u-PAR levels (P < 0.001). …”
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