Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf حسب Oliver Küppers (22742732)

"…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …"

Data Sheet 1_Artificial grassland establishment alters soil organic carbon fractions and cbbL-type carbon-sequestering microbial communities.xlsx حسب Linge Shan (22805624)

"…Compared to CK, both grassland types increased the relative abundance of Actinobacteria but decreased that of Planctomycetes. At the genus level, LG significantly enriched SinoRhizobium and MesoRhizobium, whereas GG promoted Microvirga and Bradyrhizobium.…"

Table 1_Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis.docx حسب Dongzhi Liu (2747134)

"…We also found that DC changes in the right thalamus (r = 0.241, p = 0.044), the left insula (r = 0.254, p = 0.034), and the left lingual gyrus (r = 0.275, p = 0.021) were significantly associated with higher GCS scores. …"

Data Sheet 2_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xlsx حسب Wenyong Liao (21669332)

"…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…"

Presentation 1_CD26 as a potential therapeutic target for lung adenocarcinoma.pptx حسب Wolfgang Jungraithmayr (335920)

"…Introduction<p>CD26/dipeptidyl peptidase 4 (CD26, DPP4) is a transmembrane exopeptidase that modulates tumorigenesis in different malignancies. We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …"

Table 1_CD26 as a potential therapeutic target for lung adenocarcinoma.docx حسب Wolfgang Jungraithmayr (335920)

"…Introduction<p>CD26/dipeptidyl peptidase 4 (CD26, DPP4) is a transmembrane exopeptidase that modulates tumorigenesis in different malignancies. We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …"

Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls حسب Wenyong Liao (21669332)

"…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…"

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff حسب Yulia Dwi Setia (21590591)

"…Introduction<p>Eimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.…"

Image 1_Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis.tif حسب Dongzhi Liu (2747134)

"…We also found that DC changes in the right thalamus (r = 0.241, p = 0.044), the left insula (r = 0.254, p = 0.034), and the left lingual gyrus (r = 0.275, p = 0.021) were significantly associated with higher GCS scores. …"

Image 1_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif حسب Yunlin Yang (10277429)

"…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …"

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif حسب Yunlin Yang (10277429)

"…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …"

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx حسب Yulia Dwi Setia (21590591)

"…Introduction<p>Eimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.…"

Supplementary file 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.pdf حسب Yulia Dwi Setia (21590591)

"…Introduction<p>Eimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.…"

Study group background characteristics. حسب Zicheng Hu (3825313)

"…This ratio was disrupted when blood CD4+ T-cells fell to <50 cells/μL and the CSF WBC count decreased to negligible levels; in this group the CSF:blood HIV-1 RNA ratio decreased nearly 10-fold to an overall ratio of <1:100. …"

N6-methyladenosine modification of THBS1 induced by affluent WTAP promotes Graves’ ophthalmopathy progression through glycolysis to affect Th17/Treg balance حسب Lin-na Li (20442989)

"…WTAP was significantly upregulated in CD4⁺ T cells of GO, and WTAP silencing significantly reduced m6A abundance and expression of THBS1. …"

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx حسب Mingming Xie (20963636)

"…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …"

<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b> حسب Nelly Mauras (8103110)

"…Associations with glycemic and cognitive measures were assessed.</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …"

Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip حسب Peixi Zhao (620068)

"…</p>Methods<p>Using data from the GBD 2021 data, we conducted a secondary analysis. We assessed the prevalence, mortality, and disability-adjusted life years (DALYs) of MS across 204 countries/territories from 1990 to 2021, calculating age-standardized rates.…"

Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx حسب Peixi Zhao (620068)

"…</p>Methods<p>Using data from the GBD 2021 data, we conducted a secondary analysis. We assessed the prevalence, mortality, and disability-adjusted life years (DALYs) of MS across 204 countries/territories from 1990 to 2021, calculating age-standardized rates.…"

Effect of session on winning model parameters for set size = 2 and set size = 4 for both male and females. حسب Juliana Chase (20469427)

"…Use of one-back strategy parameters changed significantly across sessions for male mice with (C) S1 “Inappropriate Lose Shift” decreasing across sessions, <i>p</i> = 0.01 (D) S2 = S4 “Stimulus Insensitive Win Stay” increasing, <i>p</i> = 0.009 and (E) S3 “Inappropriate Lose Stay” decreasing, <i>p</i> < 0.0001. …"