Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx by Zhi Shang (4849129)

“…</p>Conclusion<p>A significantly positive association was shown between systemic inflammatory indices and the risk of renal function decline in T2DM patients. …”

Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx by Alexia Giovanazzi (16816139)

“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …”

Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

“…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”

Data Sheet 1_Assessment of the effect of social media use on medical students’ academic performance: cross-sectional study from Jordan.pdf by Hana Taha (4747014)

“…GPA was significantly associated with more time spent on social media (OR: 0.476; 95%CI: 0.278–0.813; p = 0.022). …”

Passive mapping of hand motor cortex across altered states of consciousness by Yusheng Tong (6183350)

“…The sensitivity based on HGB average power at short-latency period decreased from 100% in awake stage to 72.83%±12.95%, 48.11%±15.95%, and 21.12%±5.70% across LOC stages. …”

Image 2_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of... by Xiaoqing Xia (14607269)

“…Background<p>In recent years, non-optimal temperature has significantly impacted global health including ischemic heart disease (IHD).…”

Data Sheet 1_Study of pain perception under negative emotions and its large-scale brain network dynamics in adolescents with non-suicidal self-injury.zip by Yang Zhou (65942)

“…In contrast, the occurrence frequency, coverage of microstate B, and transition probabilities from microstates C/D→B were significantly lower in the MDD group than in the HC group.…”

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff by Yulia Dwi Setia (21590591)

“…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …”

S1 Graphical abstract - by Shadi Nazarizadeh (20108029)

“…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …”

Simultaneous Determination of the Bioavailable Fraction of Eight Elements in Soil Using an Automated Extraction Device and Inductively Coupled Plasma - Optical Emission Spectrometr... by Yigang Ma (22124655)

“…Compared with manual methods, the relative standard deviation (RSD) of element detection has been significantly reduced, with values decreasing from 2.01%–23.5% to 1.54%–9.69%. …”

Data Sheet 1_Clinical characteristics and outcome of very old (≥90 years) critically ill patients with need for intensive care after surgical intervention.docx by Jöran Lücke (14948623)

“…Background<p>Due to increasing life expectancy and decreasing morbidity, society is aging. Especially the group of very old patients (≥90 years) is currently increasing significantly. …”

Table 1_High-calcium milk improves osteoporosis in postmenopausal women by regulating intestinal flora and steroid hormone biosynthesis.docx by Yanyan Zhao (211551)

“…</p>Results<p>A one-year randomized controlled trial showed that the high-calcium milk group significantly increased lumbar spine bone mineral density (L1-4 BMD), slowed bone loss in the left hip and femoral neck, elevated serum phosphorus and 25-hydroxyvitamin D levels, and modulated the bone formation marker procollagen type I N-terminal propeptide compared with the regular milk group at 6 months. 16S ribosomal ribonucleic acid sequencing showed that high-calcium milk significantly altered the β-diversity of the intestinal flora, increasing the abundance of beneficial bacteria such as Bacteroides, Oscillibacter, and Subdoligranulum, while decreasing the abundance of Firmicutes and Weissella at 12 months. …”

Image 1_Tanyu Tongzhi Formula relieves the progression of atherosclerotic plaque through lipid regulation and anti-inflammatory effects.jpeg by Tingting Chen (111216)

“…It decreased the serum levels of lipids and pro-inflammatory mediators (IL-6 and IL-1β) in AS mice. …”

Data Sheet 2_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-... by Yuchan Zhou (10928151)

“…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …”

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx by Shubin Wang (3105348)

“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. Iron overload significantly exacerbated intestinal injury in tissues, epithelial cell line, and intestinal organoids. …”

Table 1_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... by Yuchan Zhou (10928151)

“…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …”

Image 1_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”

Image 1_Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis.tif by Dongzhi Liu (2747134)

“…In the HSE group, DC values were increased in the right thalamus, the left lingual gyrus, and the right hippocampus, while they were decreased in the left insula (all p < 0.001). In our HSE cohort, the NIHSS score was significantly associated with DC changes in the right thalamus (r = −0.282, p = 0.018), the left insula (r = −0.301, p = 0.011), the left lingual gyrus (r = −0.270, p = 0.024), and the right hippocampus (r = 0.238, p = 0.047). …”