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significant potential » significant positive (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
potential decrease » potential defense (Expand Search), potential decline (Expand Search), potentially increased (Expand Search)
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20721
Minimal data sets.
Published 2025“…Moreover, GW4869 (SMase inhibitor) and evogliptin significantly reduced SMase activity in sphingomyelin (SM)-induced VSMCs as compared to both P<sub>i</sub> and SM only-treated groups. …”
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20722
Table 4_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx
Published 2025“…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …”
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20723
Data Sheet 5_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf
Published 2024“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”
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20724
Table 1_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.docx
Published 2024“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”
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20725
Data Sheet 1_Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and...
Published 2024“…Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. …”
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20726
SPIRIT Schedule of Enrollment.
Published 2025“…</p><p>Results</p><p>The EX group showed increased EMG activation for the tibialis anterior, gastrocnemius medialis, rectus femoris, and biceps femoris in both anterior-posterior (2.23 MVIC%, 95% CI: 1.13 to 3.34, p < 0.001) and posterior-anterior directions (2.35 MVIC%, 95% CI: 1.80 to 2.91, p < 0.001) compared to CO group. Onset time decreased significantly in the EX group relative to CO group (anterior-posterior: -108.07 ms, 95% CI: -117.23 to -98.89, p < 0.001; posterior-anterior: -98.72 ms, 95% CI: -106.54 to -90.90, p < 0.001). …”
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20727
Table 1_How long do pathogens persist and survive in water? A systematic review.docx
Published 2025“…Viruses averaged 22 days of survival but could persist up to 1,095 days; Human Adenovirus and Porcine epidemic diarrhea virus were the most frequently studied viral pathogens, while Human Norovirus survived over 70 days in surface water at 37°C. Viral viability decreased significantly at extreme pH levels. Parasites/protozoans, such as Cryptosporidium parvum and Giardia lamblia only showed survival duration, averaged 30 days survival, enduring extreme conditions and often benefiting from biofilm association. …”
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20728
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway
Published 2025“…</p> <p></p> <p>This schematic illustration demonstrates that PCG ameliorates LPS-elicited pulpitis by decreasing the expression of the proteins associated with the NF-κB signaling pathway and its downstream Wnt5a/ROR2 pathway and by reducing the production of inflammatory molecules.…”
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20729
The analgesic effect of total saponins of Tribulus terrestris on neuropathic pain was studied based on TLR4/NF-κB pathway
Published 2025“…ELISA was employed to detect levels of IL-1β, IL-6, and TNF-ɑ in spinal cord. CCI significantly decreased PMWT and TL. In CCI neurons and glial cells in the spinal dorsal horn were deeply stained with swelling and atrophy observed. …”
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20730
Data Sheet 2_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.xlsx
Published 2024“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”
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20731
Table 4_Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel...
Published 2024“…Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. …”
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20732
Table 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20733
Table 1_Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel...
Published 2024“…Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. …”
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20734
Table_5_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX
Published 2024“…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …”
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20735
Data Sheet 4_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20736
Table 1_Ten-year outcomes of repeat keratoplasty for optical indications.docx
Published 2025“…Cox multiple regression analysis showed male gender (p = 0.023), PK regraft (p = 0.003), regraft rejection (p = 0.003), and initial graft indications of pseudophakic bullous keratopathy (p = 0.005) and aphakic bullous keratopathy (p = 0.004) to be risk factors for regraft failure, while longer time to regraft was associated with decreased risk of failure (p = 0.013).</p>Conclusion<p>Performing EK for failed optical PK or EK significantly improved regraft survival compared to repeat PK. …”
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20737
Image 3_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif
Published 2025“…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…”
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20738
Table 5_Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel...
Published 2024“…Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. …”
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20739
Data Sheet 6_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf
Published 2024“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”
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20740
Table 1_The evolution of three-dimensional knee kinematics after ACL reconstruction within one year.docx
Published 2025“…The recovery rates and patterns differ significantly across dimensions, with some abnormalities not fully corrected within one-year post-urgery. …”