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significant potential » significant positive (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
potential decrease » potential defense (Expand Search), potential decline (Expand Search), potentially increased (Expand Search)
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18101
Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study
Published 2024“…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …”
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18102
Image 4_NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.tiff
Published 2024“…However, DMPA significantly decreased the total number of VT CD4+ and CD8+ T cells and the number of IFN-γ producing CD4 and CD8 T cells and increased the percentage of CD4 and CD8 T cells producing TNF-α compared to untreated mice. …”
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18103
Supplementary file 1_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.pdf
Published 2025“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
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18104
Data Sheet 1_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf
Published 2024“…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …”
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18105
Table 3_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xlsx
Published 2025“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
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18106
Table_1_Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19...
Published 2024“…In contrast, in the control group, the concentrations of cerebral oxygenated hemoglobin and total hemoglobin significantly decreased during left leg support (p < 0.05). …”
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18107
Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx
Published 2025“…The annual percentage change (APC) was calculated to assess the significance of temporal trends.</p>Results<p>From 1990 to 2021, global age-standardized rates of TB declined markedly, with ASIR decreasing from 173.0 to 103.0 per 100,000, ASMR from 40.0 to 14.0, and ASDR from 1,650.6 to 580.3. …”
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18108
Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx
Published 2025“…A significant increase in mRNA expression of vitamin D-responsive genes (cathelicidin, IL-10, VDR, and CYP27B1) was observed. …”
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18109
Data Sheet 1_Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood.pdf
Published 2025“…The strongest association was found between PFOA serum levels and decreased DNAm at cg06874740 (p-value<sub>Bonferroni</sub> = 2.2×10<sup>−5</sup>) and between PFOS serum levels and decreased DNAm at cg02793158 (p-value<sub>Bonferroni</sub> = 9.3×10<sup>−5</sup>). …”
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18110
Long-term impact of molecular epidemiology shifts of methicillin-resistant <i>Staphylococcus aureus</i> on severity and mortality of bloodstream infection
Published 2025“…Over this 16-year period, SCC<i>mec</i> type II decreased significantly from 79.2% to 15.5%, while type IV increased from 18.2% to 65.5%. …”
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18111
Data Sheet 1_Dangua Fang induces anti-glucolipid metabolism disorder effects similar to those of direct NFIL3 inhibition.zip
Published 2025“…The NFIL3 mRNA and protein expression levels in the serum, liver, and small intestine were significantly decreased. The relative abundance of Bacteroidota decreased, whereas that of Firmicutes increased, and changes in the gut microbiota significantly correlated with serum total cholesterol (TC), triglyceride (TG), and free fatty acid (FFA) levels. …”
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18112
Data Sheet 3_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf
Published 2024“…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …”
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18113
Supplementary Material for: Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice
Published 2025“…On day 10, db/db mice exhibited delayed wound closure, as well as impaired regeneration of the panniculus carnosus and dermis, with significantly decreased mRNA levels of VEGF and HSP90. …”
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18114
Data Sheet 2_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf
Published 2024“…During the same period, the all-cause mortality rates decreased significantly for all CGE consultations, implicating that this level of antibiotic use do not compromise patient safety. …”
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18115
Table_1_Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19...
Published 2024“…In contrast, in the control group, the concentrations of cerebral oxygenated hemoglobin and total hemoglobin significantly decreased during left leg support (p < 0.05). …”
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18116
Data Sheet 1_Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of...
Published 2025“…Background<p>Chronic hepatitis B and cirrhosis pose significant global health threats. Few studies have explored the disease burden and mortality trend of cirrhosis caused by hepatitis B virus infection among adolescents and young adults (AYAs, aged 15–39 years). …”
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18117
Table 2_Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke.xls
Published 2025“…LIPFUS + EPC exosomes groups showed a significantly decreased stroke volume on day 7, decreased FluoroJade+ cells, and significantly higher numbers of neovascularization in and around the stroke areas compared to that of other groups.…”
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18118
Data Sheet 2_Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer.zip
Published 2025“…Background<p>High-grade serous ovarian cancer (HGSOC) poses significant treatment challenges due to frequent recurrence and resistance to conventional therapies. …”
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18119
Ciliated sensory neurons and the insulin-like pathway mediated FEDUS.
Published 2024“…The seam cell division was significantly decreased in mutants that block the function of ciliated sensory neurons such as <i>daf-6(e1377)</i>, <i>xbx-1(ok279)</i>, or <i>osm-6(m201)</i>. …”
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18120
Data Sheet 2_Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of...
Published 2025“…Background<p>Chronic hepatitis B and cirrhosis pose significant global health threats. Few studies have explored the disease burden and mortality trend of cirrhosis caused by hepatitis B virus infection among adolescents and young adults (AYAs, aged 15–39 years). …”