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Novel insights into the potential role of ion transport in sensory perception in Acanthamoeba
Published 2019“…Conclusions: The present study indicates that ion transporters are involved in sensory perception of A. castellanii suggesting their value as potential therapeutic targets to block cellular differentiation that presents a significant challenge in the successful prognosis of Acanthamoeba infections.…”
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Role of Exosome in Solid Cancer Progression and Its Potential Therapeutics in Cancer Treatment
Published 2025“…These vesicles activate oncogenic pathways and can serve as biomarkers or therapeutic targets due to their role in disease modulation.</p><h3>Conclusion</h3><p dir="ltr">Exosomes play a pivotal role in solid cancer progression and offer significant potential in advancing our understanding of tumor biology. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
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The Role of AI in Drug Discovery
Published 2024“…By offering a comprehensive overview of AI′s role in drug discovery, this paper underscores the technology‘s potential to significantly enhance drug development, while also acknowledging the hurdles that must be overcome to fully realize its benefits.…”
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
Published 2019“…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …”
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Transforming Agricultural Food Waste Into Bioplastics: Methods, Potential, and Technological Advances
Published 2025“…<p dir="ltr">The improper disposal of agricultural food waste (AFW) and its associated plastic packaging significantly exacerbates environmental degradation, including pollution, greenhouse gas emissions, and loss of valuable resources, while imposing substantial economic burdens. …”