Homotransplantation of Engineered Macrophages with Surface-Modified Nanomedicines for Mitigating Myocardial Ischemia–Reperfusion Injury by Jiahui Cheng (6056966)

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Supplementary Material for: Atypical COVID-19-related Acute Macular Neuroretinopathy with Progression resulting in Severe Vision Loss by Weinberger E.M (20394746)

“…Introduction: We review the clinical course of a patient with decreased vision in the setting of COVID-19 infection consistent with an atypical presentation of acute macular neuroretinopathy (AMN). …”

Table 3_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.xlsx by Aihua Guo (13267712)

“…However, NOTCH1’s mechanisms in cervical cancer progression and radiotherapy resistance, as well as its interaction with key molecules, remain unclear.…”

Table 1_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx by Aihua Guo (13267712)

“…However, NOTCH1’s mechanisms in cervical cancer progression and radiotherapy resistance, as well as its interaction with key molecules, remain unclear.…”

Table 2_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx by Aihua Guo (13267712)

“…However, NOTCH1’s mechanisms in cervical cancer progression and radiotherapy resistance, as well as its interaction with key molecules, remain unclear.…”

The volume of the right (red) and left (blue) IC are shown as a function of age on a logarithmic scale. by Pingling Kwok (14896191)

The small blue circles show the IC-volume (mean of left and right) from 72 males and the small red squares from 51 females as a function of age. by Pingling Kwok (14896191)

Prediction of the effect of the 9 nsSNPs on AKT2 proteins’ structure and function by eight computational tools. by Sadia Afrin Runa (22504971)

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Distribution of SNPs and their frequencies based on mutation classes. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Capivasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Ipatasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Akt1/Akt2-IN-1 (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Predicted pathogenicity of R274H, Y265N, and R467W substitutions and their molecular mechanisms. by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Akt1/Akt2-IN-1 through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Capivasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Binding affinity of Akt1/Akt2-IN-1, Capivasertib, and Ipatasertib with AKT2 (wild and mutants) protein. by Sadia Afrin Runa (22504971)

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Superimposed structures of AKT2 native (green color) and mutant (red color) models to visualize the stereochemical conformation of wild type and mutant residues at (a) 274, (b) 265... by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Ipatasertib complex through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Ipatasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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