Image 1_Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice.jpeg حسب Chun Li (57810)

"…Introduction<p>Infection with Clonorchis sinensis (C. sinensis) has the potential to induce liver fibrosis and significantly alter the gut microbiota. However, it remains unclear how these changes in the gut microbiota, through the gut-liver axis, influence the progression of liver fibrosis. …"

Image 3_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…MNAM supplementation accelerated ARHL in both strains, with B6 mice showing more pronounced and earlier disease progression. Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…MNAM supplementation accelerated ARHL in both strains, with B6 mice showing more pronounced and earlier disease progression. Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

Image 2_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…MNAM supplementation accelerated ARHL in both strains, with B6 mice showing more pronounced and earlier disease progression. Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

Image 1_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…MNAM supplementation accelerated ARHL in both strains, with B6 mice showing more pronounced and earlier disease progression. Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…MNAM supplementation accelerated ARHL in both strains, with B6 mice showing more pronounced and earlier disease progression. Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. حسب Katharine Striedinger (15503387)

"…<p><b>(a)</b> Quantification of protein expression for PAX7+ and MYOD1 positive HuMuSC at day 0, 3 and 6 in vitro, showing an inverse correlation as progressively PAX7 expression decreases and MYOD1 expression increases in HuMuSC as they activate <i>in vitro</i>. …"

<b>Differential Myopathic and Transcriptomic Changes in Soleus and Gastrocnemius Muscles in a Novel Chronic Hindlimb Ischemia Rat Model Induced by Endovascular Catheter Occlusion</... حسب Hanjun Wang (21595280)

"…Histological analysis revealed that IFCO significantly increased levels of fibrosis and decreased myofiber cross-sectional area, in the soleus only. …"

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf حسب Rongrong Huang (819212)

"…To elucidate the mechanisms of viral pneumonia progression and potential targets for its treatment.…"

Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis حسب Jianan Feng (11178007)

"…<p>Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. …"

Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of <i>Muc4</i> حسب Zhong-Tang Li (21183172)

"…Then, the results of transcriptomic analysis and <i>in vivo</i> and <i>in vitro</i> experiments revealed that expression of Mucin 4 (MUC4) was significantly decreased at the transcriptional and protein levels in tubular HIF-1α-knockout mice. …"

Supplementary file 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …"

Table 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.docx حسب Chao Li (145513)

"…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …"

Table 2_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... حسب Qi Sun (127)

"…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …"

Supplementary file 2_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …"

Table 1_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... حسب Qi Sun (127)

"…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …"

Supplementary file 3_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Knockdown of SRSF1 significantly decreased expression of full-length MYO1B protein in drug-resistant BC cells (P < 0.05). …"

<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b> حسب Ji-Seok Kim (21287672)

"…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …"

Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg حسب Shenglan He (7641308)

"…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …"

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf حسب Wei Gong (112494)

"…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …"