Supplementary file 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machi... by Zhiyuan Gong (51844)

“…</p>Results<p>Gene expression analysis revealed dynamic changes during COVID-19 progression. Adaptive immune cells (e.g., B cells and T cells) decreased, while innate immune cells (e.g., monocytes and neutrophils) increased, particularly in ICU patients. …”

Table 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning.x... by Zhiyuan Gong (51844)

“…</p>Results<p>Gene expression analysis revealed dynamic changes during COVID-19 progression. Adaptive immune cells (e.g., B cells and T cells) decreased, while innate immune cells (e.g., monocytes and neutrophils) increased, particularly in ICU patients. …”

Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

“…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …”

Data collected from pregnant women for the analysis of placental anemia, placental malaria, Cytokines and birth anthropometric indices by Bamgboye Morakinyo Afolabi (16838970)

“…Women leaving in malaria endemic areas are at high risks for malaria infections and they might acquire significant clinical immunity before pregnancy, and placental malaria, though often asymptomatic, could have harmful effects on the fetus [10]. …”

Image2_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF by J Bundy (19843944)

“…Moreover, this GABA_AR mediated Cl⁻ flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA_A β3 subunit knockdown. …”

Data Sheet 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatic... by Yongjing Li (3821944)

“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”

Table 3_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”

Data Sheet 1_Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy.pdf by Sindhuja Sivanandham (13851914)

“…</p>Results<p>Sphingomyelins (SM) and lactosylceramides (LCER) increased during acute infection, returning to baseline during chronic infection; Hexosylceramides (HCER) increased throughout infection, being normalized with prolonged ART; Phosphatidylinositols (PI) and lysophosphatidylcholines (LPC) decreased with SIV infection and did not return to normal with ART; Phosphatidylethanolamines (PE), lysophosphatidylethanolamines (LPE) and phosphatidylcholines (PC) were unchanged by SIV infection, yet significantly decreased throughout ART. …”

Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF by J Bundy (19843944)

“…Moreover, this GABA_AR mediated Cl⁻ flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA_A β3 subunit knockdown. …”

Image 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”

Table 2_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”

Table 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne... by Yongjing Li (3821944)

“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”

Clinical observation and immune effect of high-intensity focused ultrasound (HIFU) treatment on patients with colorectal cancer liver metastasis by Shasha Wang (346796)

“…Post-treatment serum IL-6 levels decreased significantly (<i>p</i> < 0.001). OS was significantly better in the HIFU + chemotherapy group compared to chemotherapy-only (<i>p</i> < 0.0001).…”

Image 1_Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice.jpeg by Chun Li (57810)

“…</p>Results<p>The abundance of R. bromii increased during the inflammatory stage of C. sinensis infection and decreased significantly during the fibrosis stage. …”

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. by Katharine Striedinger (15503387)

“…<p><b>(a)</b> Quantification of protein expression for PAX7+ and MYOD1 positive HuMuSC at day 0, 3 and 6 in vitro, showing an inverse correlation as progressively PAX7 expression decreases and MYOD1 expression increases in HuMuSC as they activate <i>in vitro</i>. …”

Table 1_Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study.docx by Runchuan Gu (10911582)

“…The particle distribution between the different BOS grades had a similar pattern; however, it significantly decreased PFR with severity in the BOS grade.…”

Data Sheet 1_China’s readiness for transitioning to a low-carbon economy: mitigant and catalyst factors for a geopolitical conflict.zip by Yan Chen (4308)

“…We use a qualitative analysis to identify that rising GPR, exacerbated by market instability, resource allocation conflicts, and trade disputes, significantly hinders LCED progress. However, these geopolitical tensions also act as a catalyst for accelerating the development of renewable energy, reducing reliance on traditional energy sources, and fostering low-carbon technologies. …”

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf by Rongrong Huang (819212)

“…To elucidate the mechanisms of viral pneumonia progression and potential targets for its treatment.…”

Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis by Jianan Feng (11178007)

“…<p>Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”