Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents by Yujuan Li (554062)

“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”

mAP0.5 Curves of various models. by Yaojun Zhang (389482)

“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”

Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure by figshare admin karger (2628495)

“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”

Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Data Sheet 12_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Network loss function change diagram. by Yaojun Zhang (389482)

“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”

Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”

Dust particle flow trace diagram. by Yuxuan Liu (349237)

“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”

Adverse events in patients with castration-resistant prostate cancer treated with ra-223: a retrospective pharmacovigilance study by Lei Yang (102719)

“…Four sequential analysis strategies were employed to assess the significance of these AEs.</p> <p>In total, 4,228 Ra-223-related AE reports were identified in the FAERS database. …”

Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”

Model inputs. by Mingxi Xie (19812594)

“…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …”

Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy by Jiayu Zhang (128702)

“…Functional studies demonstrated that the conditioned medium from HG-exposed MG significantly enhanced endothelial cell proliferation, migration, and tube formation. …”

Discrete phase parameter setting. by Yuxuan Liu (349237)

“…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”

Data Sheet 3_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

“…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”

Comparative diagrams of different indicators. by Yaojun Zhang (389482)

“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”

Table 1_Case report: Treatment of severe phorate poisoning.xlsx by Wang Kunlun (21287522)

“…In the follow-up treatment, the concentration of five metabolites gradually decreased. The concentration of the phorate sulfoxide and phorate sulfone rebounded with the suspension of HP, but that of the other metabolites did not rebound. …”

Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress by Serina Yan (22416354)

“…Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …”

Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

“…Lipid metabolism was significantly altered in moderate-altitude athletes, including pathways such as linolenic and linoleic acid, sphingolipid, and arachidonic acid, as well as processes involving the transfer of acetyl groups into mitochondria and fatty acid biosynthesis. …”

Image 2_Modulation of VR-HMD-induced cybersickness using cathodal transcranial direct current stimulation: a functional near-infrared spectroscopy study.jpeg by Seong Ho Yun (22686965)

“…Results showed that cathodal tDCS significantly reduced nausea-related cybersickness symptoms compared to sham stimulation (p < 0.05). fNIRS analysis revealed decreased oxyhemoglobin concentrations in the bilateral superior parietal lobule and angular gyrus following cathodal tDCS, indicating reduced cortical activity in these regions. …”