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    ASP protects the AC16 cells from DOX-induced cardiotoxicity via Nrf2 activation. by Xueyang Bai (20550422)

    Published 2025
    “…<p>(A) Representative images of protein expression detected by Western blot of p-PI3K,p-AKT, AKT, and the Nrf2 downstream signaling pathways in AC16 cells; (B, C) ML385 does not affect PI3K/AKT (n = 3); (D-F) The statistical results show that ML385 significantly represses NRF2 activation, leading to a decrease in its downstream gene expression (n = 3); (G, H) Lipid ROS levels (n = 3); (I, J) Quantitative q-PCR analysis of relative ANP and BNP mRNA expression (n = 3); (K, L) Representative images (Scale bar =  100 μm) and statistical analysis of JC-1 (n = 150); One-way ANOVA (Tukey post-test), means ±  SD. …”
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