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18541
DESeq output data for all comparisons.
Published 2025“…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”
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18542
Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx
Published 2025“…After full adjustment for covariates, mLE8 exhibited a significant mediating role in the associations of both DI-GM (14.46% mediated effect, p < 0.001) and DI-GM beneficial (12.99% mediated effect, p < 0.001) with sleep disorders. …”
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18543
Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…Conversely, PTEN expression was found to be decreased. Additionally, autophagy-related protein levels were diminished while anti-apoptotic protein expression was markedly elevated (P < 0.01). …”
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18544
Supplementary Material for: Identification of risk factors associated with metabolic dysfunction-associated steatotic liver disease in psoriatic patients
Published 2024“…There was no significant difference between the mean age of both patient groups (50.4 vs 47.3 years, p=0.26). …”
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18545
Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx
Published 2025“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”
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18546
Model index comparison.
Published 2024“…The factors within the Park attributes (G1) and the park’s social media level (G4) showed a two-way interaction strength increase. (4)The coefficients of influence of impact factors on the space heterogeneity of vacation park vitality exhibit significant variation. The positive indicators have a spatial distribution that decreases from the northwest to the southeast, with the old city district having higher coefficients than the new city district. …”
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18547
Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat...
Published 2025“…PSCK9 inhibitors and potent statins significantly reduced LDL-C levels from baseline vs. placebo regardless of background therapy. …”
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18548
'Plan-B': Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes
Published 2025“…One-third of respondents reported already experiencing significant impact from funding changes, while over two-thirds expressed high concerns about future effects. …”
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18549
Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis...
Published 2024“…Despite global declines in IHD incidence over the last three decades, decreasing trends in incidence have slowed and, in some countries, flattened. …”
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18550
Table 1_Impact of short-term (24 h) blood pressure variability on 30-days clinical outcomes of acute strokes at two tertiary hospitals in Dar-es-Salaam.docx
Published 2025“…Functional outcomes improved significantly by day 30: the Barthel Index increased, and mRS scores decreased. …”
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18551
Table 1_The effect of Traumeel LT ad us. vet. on the perioperative inflammatory response after castration of stallions: a prospective, randomized, double-blinded study.docx
Published 2024“…All stallions had the highest pain summary score 8 hours after surgery, with decreasing values thereafter. The pain scores were not statistically different at any time point. …”
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18552
Data Sheet 1_Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.docx
Published 2024“…Other sleep structure and sleep-respiratory parameters did not differ significantly between the two groups. Subjective sleep quality was slightly improved with dexmedetomidine on the night of surgery, but not statistically significant (median difference, 6; 95% CI, 0 to 13; p = 0.060). …”
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18553
Image 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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18554
Internal states adjust the Brp compartmental heterogeneity through octopamine.
Published 2025“…*<i>P</i> < 0.05 and ns = not significant. The data underlying this Figure can be found in S1 Data.…”
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18555
Evolutionarily conserved and functionally important amino acids in Artemis.
Published 2025“…<i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.</p>…”
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18556
Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma
Published 2025“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”
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18557
SEAwise Report on the impacts of fisheries on stocks and landings under SEAwise EBFM
Published 2025“…The ecosystem model generally showed less optimistic outcomes under climate change, with significant decreases in biomass and catches in both the Celtic and North Seas. …”
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18558
Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5).
Published 2025“…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …”
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18559
Table2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx
Published 2024“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
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18560
Table13_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx
Published 2024“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”