Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses حسب Mohammed I. Danjuma (13569767)

"…<h3>Background</h3><p dir="ltr">Despite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine in patients with Coronavirus Disease 2019 (COVID-19) clinical syndrome.…"

Design and Evaluation of a Just-in-Time Adaptive Intervention (JITAI) to Reduce Sedentary Behavior at Work: Experimental Study حسب Tasnim Ismail (18418554)

An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity حسب Wang, Wei

"…Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. …"
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Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients حسب Swapna Thomas (17337925)

"…Vaccinating diabetic patients against influenza would significantly reduce hospitalization due to disease severity. …"

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases حسب Mazhar Pasha (11197767)

"…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…"

Being female with vitiligo disease in traditional societies within North Africa حسب Mohamed Faraj Saleh Raheel (21633068)

"…However, the illness profoundly impacted patients’ lives emotionally, with clear consequences, including diminished emotional satisfaction and reduced social participation. The results of this study highlight the negative effects that vitiligo disease can have on women’s quality of life within traditional Libyan society. …"

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase حسب Ahmed S. Ibrahim (10049522)

Air pollution burden of disease over highly populated states in the Middle East حسب Rima J. Isaifan (8350056)

"…</p><h3>Conclusions </h3><p dir="ltr">The results indicate a significant impact of air pollution due to long-term exposure to fine particles resulting in early mortality. …"

Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing حسب Sulaiman Khan (12585349)

"…It contains a gigantic amount of data, especially a plethora of data types that has been significantly useful in diverse research domains. In healthcare domain, the researchers use computational devices to extract enriched relevant information from this data and develop smart applications to solve real-life problems in a timely fashion. …"

Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity حسب Rukaya Basala

"…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …"
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease حسب Ramadan, Wijdan H.

"…For patients not sufficiently controlled on a single long-acting bronchodilator, a combination of different bronchodilators has shown a significant increase in lung function. Tiotropium, a once-daily dosing LAMA, demonstrated sustained improvements in lung function as well as improved health-related quality of life, reduced exacerbations, and increased survival without altering the rate of decline in the mean forced expiratory volume in 1 second (FEV1) with fairly tolerable side effects. …"
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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease حسب Sudharsana Sundarrajan (3181371)

"…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …"

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

"…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …"

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Further treatment with 200 nM Ex-4 for 3 h significantly reduced the OA-induced lipid accumulation (p < 0.05). …"

The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis حسب Yasamin Abdu (15899155)

"…Notably, the increased bleeding risk observed seldom had clinical significance. We recommend individualizing management strategies, considering the overall positive impact of transfusions in reducing complications. …"

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study حسب Shubham Chauhan (21334742)

"…While prevalence rates experienced a minor decline, Disability‐Adjusted Life Years (DALYs) rose from 272.02 to 308.27 per 100,000, reflecting an increasing burden of the disease. Notably, Nepal significantly reduced its incidence rates, while Pakistan saw an increase in mortality rates. …"

Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease حسب El Maarri, Osman

"…Pancreatic tumors are usually diagnosed at an advanced stage in the progression of the disease, thus reducing the survival chances of the patients. …"
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An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... حسب Khreibi, Rima Abou

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Effectiveness of Project Management Office (PMO) in UAE Context: Exploring the Link between Meeting the Critical Success Factors (CSFs) of Central Enterprise PMO and its Added Valu... حسب Fatah, Emad Elsayed Abdel Halim Abdel

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Favipiravir for the treatment of coronavirus disease 2019 pneumonia; a propensity score-matched cohort study حسب Rand A. Alattar (9538554)