Baseline characteristics of participants. حسب Mei Zhou (269746)

"…Statistical analyses comprised descriptive statistics, t-tests, chi-square tests, multiple linear regression, and multivariate logistic regression.</p><p>Results</p><p>After DRG implementation, the logarithmic mean of total hospitalization expenditures decreased significantly (3.914 ± 0.837 vs. 3.872 ± 1.004), while rates of unplanned readmissions, unplanned reoperations, postoperative complications, and patient complaints within 30 days increased significantly (3.784% vs 4.214%, 0.083% vs 0.166%, 0.207% vs 0.258%, 3.741% vs 5.133%). …"

The framework diagram of this study. حسب Mei Zhou (269746)

"…Statistical analyses comprised descriptive statistics, t-tests, chi-square tests, multiple linear regression, and multivariate logistic regression.</p><p>Results</p><p>After DRG implementation, the logarithmic mean of total hospitalization expenditures decreased significantly (3.914 ± 0.837 vs. 3.872 ± 1.004), while rates of unplanned readmissions, unplanned reoperations, postoperative complications, and patient complaints within 30 days increased significantly (3.784% vs 4.214%, 0.083% vs 0.166%, 0.207% vs 0.258%, 3.741% vs 5.133%). …"

Image 2_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

"…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"

Image 1_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

"…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"

Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer حسب Lisa N. Chesner (19677087)

"…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …"

Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer حسب Lisa N. Chesner (19677087)

"…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …"

Table 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Image 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx حسب Ping-Heng Zhang (21785162)

"…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …"

Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx حسب Na Zhu (331131)

"…After adjusting for all confounders, LC9 was significantly and negatively associated with both MASLD (OR = 0.59, 95% CI: 0.54–0.64) and hepatic fibrosis (OR = 0.66, 95% CI: 0.45–0.97), with each 10-point increase in the LC9 score decreasing the prevalence by 41% and 34%, respectively. …"

Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia حسب Bros Doeurk (21163097)

"…Bionomic parameters were measured from hatching rate of F2 eggs until number of F3 eggs, in triplicate for each temperature treatment.</p><p dir="ltr"><b>Results</b>: Temperature significantly influenced all life-history traits of <i>Ae. aegypti</i> and <i>Ae. albopictus</i>. …"

Image 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx حسب Juanzhao Cao (22651742)

"…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.</p>…"

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx حسب Zhijie Zhuang (17669958)

"…Sample-weighted multivariable linear regression models were used to examine the association between MDS and serum Klotho levels, adjusting for age, sex, race, socioeconomic status, lifestyle factors (smoking, alcohol use), clinical parameters (body mass index, blood pressure, lipid levels), and energy intake.</p>Results<p>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg.…"

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif حسب Marcela Rios-Carlos (22759823)

"…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …"

S1 Raw data - حسب Dao-Cheng Zhou (20314697)

"…All-cause and CVD mortality gradually decreased with increasing ideal LE8 metrics. LE8 was not significantly associated with cancer mortality. …"

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf حسب Mengyuan Dai (9747317)

"…Subsequently, an OA model in rats was induced by intra-articular injection of monoiodoacetic acid (MIA), and EGCG was administered for OA treatment to validate the expression of the differentially expressed genes.</p>Results<p>EGCG could reduce reactive oxygen species (ROS) levels and decreased the expression of inflammatory cytokines IL-β, MMP13, and TNF-α. …"

Image 4_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Table 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"