Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx by Yajie Hu (550783)

“…To determine whether IP-10 influences BBB integrity, we examined junctional complexes. Our results revealed that the expression levels of Claudin5, Occludin, ZO-1 and VE-Cadherin were notably decreased in CV-A16-infected HUVECs, but these indicators were restored in CV-A16-infected HUVECs with Eldelumab treatment. …”

Image 1_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

Image 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

Image 8_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…This quantification was also performed in HGFs with suppressed Cav-1 expression using western blotting.</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 2_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…This quantification was also performed in HGFs with suppressed Cav-1 expression using western blotting.</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Table 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…Tyrosine hydroxylase positive neurons were labeled with immunofluorescence, and tyrosine hydroxylase levels were detected by Western blot (WB) assay.</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…Tyrosine hydroxylase positive neurons were labeled with immunofluorescence, and tyrosine hydroxylase levels were detected by Western blot (WB) assay.</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…The estimated annual percentage change (EAPC) is used to assess the temporal dynamics of the disease burden, and the relationship between the disease burden and the sociodemographic index (SDI) is explored.</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. …”

Data Sheet 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

Supplementary file 1_Metal ion-enhanced photosynthetic bacteria for bioplastic production from kitchen waste digestate: performance and mechanism.docx by Wei Zhao (14321)

“…</p>Conclusion<p>The concentration of 10 mg/L Fe³⁺ and 2 mg/L Mn²⁺ significantly enhanced PSB biomass and PHB accumulation (p < 0.05). …”

Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Data Sheet 3_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…Tyrosine hydroxylase positive neurons were labeled with immunofluorescence, and tyrosine hydroxylase levels were detected by Western blot (WB) assay.</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

RtcB cooperates with its cofactor Archease to promote axon regeneration. by Qin Wang (109812)

“…(D and E) Compared with <i>RtcB</i>^<i>1-4B</i> or <i>Archease</i>^<i>PB</i> heterozygotes, axon regeneration is significantly decreased in <i>RtcB</i> and <i>Archease</i> transheterozygotes. …”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Pilo-SE decreased intact kininogen levels in the hippocampus and increased cleaved to intact kininogen (cHK / iHK) ratio. …”

Table 5_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…Tyrosine hydroxylase positive neurons were labeled with immunofluorescence, and tyrosine hydroxylase levels were detected by Western blot (WB) assay.</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table 1_Assessment of various salt water stresses with mineralization on plant growth and antioxidants activity to regulate oxidative stress and ROS scavenging of halophyte ice pla... by Xinchao Ma (22249096)

“…The specific configuration method of the composite saline-alkali solution is to mix Na₂SO₄, NaCl, NaHCO₃, CaCl₂, MgCl₂ in the proportion of 8:8:1:1:1 on the basis of distilled water. The results indicated that the T6 treatment (saline-alkali solution of 30 g/L) strongly decreased the plant height, stem thickness, leaf area and SPAD value of ice plants, and obviously suppressed the shoot and root biomass with the increase in salinity. …”