Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip by Fulai Tu (15364489)

“…Data collation and visualizations were conducted using R software, with statistical significance established at a p-value threshold of 0.05.…”

Supplementary file 1_Global burden of HIV, syphilis, and HBV infection among women of childbearing age and children under five: based on the Global Burden of Diseases Study 2021.do... by Jia Lian (9469818)

“…Generally, ASPR and ASIR decreased as the sociodemographic index (SDI) increased. …”

Data Sheet 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip by Li Cui (37567)

“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Table5_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx by J. Riera-Arnau (20431328)

“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”

Data Sheet 1_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf by Diana Maltseva (11678641)

“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”

Data Sheet 1_Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer.docx by Bridget E. Crossman (18230326)

“…Flow cytometry, immunohistochemistry, RNA, multiplex ELISA, immunohistochemistry and multiplex immunofluorescence analysis were used to probe the effects of MerTK expression on the tumor immune microenvironment.</p>Results<p>Overexpression of MerTK in TNBC syngeneic mouse models leads to a marked delay in tumor growth, coupled with significant increases in anti-tumor M1 macrophage, CD4+ T cell, active CD8+ T cell, active NK cell, and NKT cell populations. …”

Data Sheet 1_How vanadium and manganese compounds impact cardiac mitochondrial function.pdf by Connor C. Dolan (21556343)

“…Metal speciation calculations were performed to predict the chemical species present under biological assay conditions.</p>Results and Discussion<p>Both vanadium and manganese salts decreased rates of mitochondrial respiration in a concentration dependent manner, which was attenuated when the metals were complexed to an organic ligand. …”

Table 2_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... by Jiaochen Luan (9704384)

“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”

Data Sheet 3_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …”

Data Sheet 1_The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients.docx by Qiuyue Long (11381148)

“…The single-cell RNA sequencing (scRNA-seq) was applied to characterize the critical cell subset associated with prognosis and elucidate its phenotype in COVID-19.</p>Results<p>We revealed a significant increase in CD38⁺HLA-DR⁺ T cells in non-survivor COVID-19 patients, establishing them as an independent risk factor for 28-day mortality. …”

Supplementary Material for: The efficacy of hemoperfusion in severe COVID-19 patients: A systematic review and meta-analysis by figshare admin karger (2628495)

“…There was no statistically significant difference in mortality between the hemoperfusion and the control groups (RR 0.81 95%CI[0.71, 0.93]; p = 0.15 > 0.05; I2 = 68.2%). …”

Image 2_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg by Amy Fagan (17678004)

“…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …”

Data Sheet 4_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …”

Baseline characteristics of the study population. by Vatsala Rajendram (20691806)

“…This sub-analysis measured trough levels of measles neutralising antibodies using a Vero cell-based measles virus neutralisation assay.</p><p>Results</p><p>Median measles antibody trough levels were ~ 1300 mIU/mL with no significant difference between Gammaplex 5% and Gammaplex 10% treatment (p >  0.9) or the 21-day or 28-day dosing regimen (p >  0.3). …”

Table3_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx by J. Riera-Arnau (20431328)

“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”

Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx by Wenshuai Zheng (21641225)

“…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …”

DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf by Bo Yao (308010)

“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”

Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... by Pengyu Wang (6680312)

“…Finally, WB and qPCR were performed to validate the mechanism of dapagliflozin on diabetic liver injury in vivo and in vitro.</p>Results<p>Dapagliflozin alleviated diabetic liver injury by decreasing lipid deposition, oxidative stress levels, the inflammatary and apoptosis-related proteins and mRNA levels, while it also reducing blood glucose. …”

Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png by Li Cui (37567)

“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”