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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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17481
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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17482
Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor...
Published 2025“…In addition, we examined the association between high body mass index (BMI) exposure and PCOS, including its comorbidity burden across different age groups, taking into account regional variations in high BMI exposure.</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”
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17483
Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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17484
Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX
Published 2024“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”
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17485
Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b...
Published 2025“…In addition, we examined the association between high body mass index (BMI) exposure and PCOS, including its comorbidity burden across different age groups, taking into account regional variations in high BMI exposure.</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”
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17486
Image3_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg
Published 2024“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”
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17487
DataSheet1_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.docx
Published 2024“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”
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17488
Table1_Age and gender influence on clinical manifestations of thyroid-associated ophthalmopathy: a case series of 2479 Chinese patients.xlsx
Published 2024“…Background<p>Significant individual differences exist in the clinical manifestations of thyroid-associated ophthalmopathy (TAO). …”
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17489
Image1_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg
Published 2024“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”
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17490
Image2_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg
Published 2024“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”
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17491
DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx
Published 2024“…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …”
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17492
Using insects for sustainable waste management of superabundant animals
Published 2025“…However, sterilization did not have a significant effect neither in the body weight nor in the lifespan of adults. …”
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17493
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS
Published 2025“…NEMP exposure induced damage to both GC-1 and TM-3 cells, resulting in decreased cell viability and increased apoptosis rates. …”
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17494
Data Sheet 1_Laser diode irradiation mitigates salt stress in rice through coordinated physiological and molecular responses.docx
Published 2025“…Correspondingly, oxidative damage markers were significantly reduced, with H<sub>2</sub>O<sub>2</sub> and MDA levels decreased while proline accumulation increased. …”
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17495
Beyond species richness: grazing and fertilization shape temperate grassland stability through distinct stabilizing effects
Published 2025“…Alterations in land use, particularly grazing and fertilization, pose significant threats to the stability of grassland ecosystems. …”
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17496
Assessing the biochemical and genotoxic effects of low intensity 2.45GHz microwave exposure on <i>Arabidopsis thaliana</i> plants
Published 2024“…Leaf morphological parameters exhibited no significant alterations during this brief exposure period. …”
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17497
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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17498
Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se...
Published 2024“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”
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17499
Image 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif
Published 2025“…These subtypes exhibited significantly different distributions between AF and SR. …”
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17500
Table 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx
Published 2025“…These subtypes exhibited significantly different distributions between AF and SR. …”