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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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18361
Table 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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18362
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Published 2025“…Genetic or chemical inhibition of ELOVL6 results in decreased proliferation and migration, accompanied by alterations in fatty acid elongation. …”
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18363
Image 2_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif
Published 2025“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”
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18364
Image3_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.TIF
Published 2025“…</p>Methods<p>Molecular, morphological, and neurophysiological assays were used to investigate the neuroprotective effects of C16 peptide and related signaling pathways in a model of EAE.</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”
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18365
Image7_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG
Published 2025“…</p>Methods<p>Molecular, morphological, and neurophysiological assays were used to investigate the neuroprotective effects of C16 peptide and related signaling pathways in a model of EAE.</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”
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18366
Image9_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG
Published 2025“…</p>Methods<p>Molecular, morphological, and neurophysiological assays were used to investigate the neuroprotective effects of C16 peptide and related signaling pathways in a model of EAE.</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”
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18367
Image 3_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif
Published 2025“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”
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18368
Table 13_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.docx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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18369
Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf
Published 2024“…Furthermore, we found that the increased risk of OSA could be attributed to reduced levels of X-11849 and X-24978 (decreases of 7.1% and 8.4%, respectively). Sensitivity analysis results supported the reliability of these findings.…”
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18370
Table1_Protective effect of Huanglian Pingwei San on DSS-induced ulcerative colitis in mice through amelioration of the inflammatory response and oxidative stress.DOC
Published 2024“…The protein expression in the colonic tissue was validated via immunohistochemistry (IHC) and Western blotting.</p>Results<p>HLPWS significantly improved UC symptoms and colon tissue histology in mice. …”
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18371
Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif
Published 2025“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”
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18372
Table 1_The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuate Pseudomonas aeruginosa virulence.docx
Published 2025“…In vitro, C-PC reduced the adhesion and invasion of PA2 in RAW264.7 cells, and decreased LDH release and macrophage damage caused by PA2 infection. …”
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18373
Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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18374
Data Sheet 1_Development of subjective well-being in adolescents before and during the COVID-19 pandemic.pdf
Published 2025“…However, during the COVID-19 pandemic, only satisfaction with family decreased significantly. Among the moderators, especially the socioeconomic status indicated interindividual differences in the variation of different SWB facets.…”
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18375
Data Sheet 3_Postural correlates of visual incentives: application to food and alcohol stimuli.pdf
Published 2025“…After the experiment, participants rated each stimulus on pleasantness, unpleasantness, consumption, approach, avoidance, and intensity.</p>Results<p>Subjective ratings differed significantly between conditions. …”
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18376
Data Sheet 2_Postural correlates of visual incentives: application to food and alcohol stimuli.pdf
Published 2025“…After the experiment, participants rated each stimulus on pleasantness, unpleasantness, consumption, approach, avoidance, and intensity.</p>Results<p>Subjective ratings differed significantly between conditions. …”
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18377
Data Sheet 1_Postural correlates of visual incentives: application to food and alcohol stimuli.pdf
Published 2025“…After the experiment, participants rated each stimulus on pleasantness, unpleasantness, consumption, approach, avoidance, and intensity.</p>Results<p>Subjective ratings differed significantly between conditions. …”
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18378
Data Sheet 2_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf
Published 2025“…Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”
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18379
Data Sheet 1_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf
Published 2025“…Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”
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18380
Comparative metabolome analysis of case (fearful dogs) versus controls.
Published 2025“…The red and green dots represent the significant increased and decreased metabolites, respectively. …”