<b>Exercise alters molecular profiles of inflammation and substrate metabolism in human white adipose tissue</b> by Maria Pino (6944198)

“…<p dir="ltr">White adipose tissue (WAT) plays a significant role in whole-body energy homeostasis, and its excess typifies obesity. …”

<b>Two therapeutic approaches for vancomycin-induced acute kidney injury: urinary acidification or inhibition of organic anion transporters with probenecid</b> by Thibault Le Moulec (20854373)

“…Urinary acidification decreased plasma urea and improved histological scores of acute tubular necrosis (ATN) and cast formation on the third day. …”

Data Sheet 1_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx by Marlene Saban (20349744)

“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. Following analysis of the participant interviews four themes emerged. …”

DataSheet1_The Impact of Unmet Healthcare Needs on the Perceived Health Status of Older Europeans During COVID-19.pdf by Šime Smolić (15918211)

“…Mixed-effects logistic regression analysis was employed to explore SRH deterioration during the pandemic.</p>Results<p>Findings indicate that unmet healthcare needs decreased throughout the pandemic but significantly contributed to the worsening of SRH among older adults. …”

Manuscript FAM22 for submission.docx by Mehmet Bilen (21219992)

“…Furthermore, the total ash generation decreased bottom ash by 9.4% and fly ash by 17.6%, while hot water production rose by approximately 8.2%. …”

Table 1_Epicatechin gallate and its analogues interact with sortase A and β-lactamase to suppress Staphylococcus aureus virulence.docx by Fei Teng (201085)

“…ECG did not affect the expression of sortase A or β-lactamase but significantly alleviated the cytotoxicity of S. aureus USA300. …”

Data Sheet 1_Sympathetic vasomotion as an early marker of hemorrhage.docx by Peter Ricci Pellegrino (22695710)

“…After a two-week recovery period, conscious rabbits then underwent controlled blood withdrawal via an auricular arterial catheter to simulate hemorrhage.</p>Results<p>Vasomotion differences between innervated and denervated kidneys in admittance gain, phase shift, and coherence increased significantly prior to increases in heart rate or decreases in blood pressure.…”

Data Sheet 2_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx by Marlene Saban (20349744)

“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. Following analysis of the participant interviews four themes emerged. …”

Additional file 11 of Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma by Benjamin Lin (120565)

“…Of these categorized genes, 980 and 844 are significantly (DESeq2 FDR < 0.05 and LFC > 1) increased and decreased after treatment with either drug (C). …”

Table 1_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…To further examine the dose–response relationship, restricted cubic spline models were employed to assess potential non-linear associations.</p>Results<p>Increased total physical activity [hazard ratio (HR) = 0.978; 95% confidence interval (CI): 0.961–0.995, P = 0.011], moderate-to-vigorous PA (HR = 0.960; 95% CI: 0.929–0.992, P = 0.014), and moderate physical activity (MPA) (HR = 0.953; 95% CI: 0.918–0.990, P = 0.014) were significantly associated with a decreased risk of major adverse cardiovascular events, respectively. …”

Table 2_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…To further examine the dose–response relationship, restricted cubic spline models were employed to assess potential non-linear associations.</p>Results<p>Increased total physical activity [hazard ratio (HR) = 0.978; 95% confidence interval (CI): 0.961–0.995, P = 0.011], moderate-to-vigorous PA (HR = 0.960; 95% CI: 0.929–0.992, P = 0.014), and moderate physical activity (MPA) (HR = 0.953; 95% CI: 0.918–0.990, P = 0.014) were significantly associated with a decreased risk of major adverse cardiovascular events, respectively. …”

Table 1_The health burden of disease attributable to low calcium intake: a comprehensive analysis of trends and socioeconomic impacts from 1990 to 2021.docx by Yanping Wang (275956)

“…Furthermore, Bayesian age-period-cohort (BAPC) modeling was applied to forecast trends spanning 2022–2050.</p>Results<p>From 1990 to 2021, global colon and rectum cancer (CRC)-related deaths tied to DLC rose from 57,363 to 89,089, while the ASMR decreased from 1.54 to 1.06 per 100,000 [EAPC = −1.33 (95% CI: −1.37 to −1.29)]. …”

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv by Jie Zheng (31208)

“…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …”

Data Sheet 1_Wedelia trilobata-derived biochar mitigates chromium toxicity and improves physiological performance in hydroponically grown Chinese cabbage.docx by Fengyue Qin (21748557)

“…Additionally, the malondialdehyde (MDA) content decreased by 29.66% in roots and 15.98% in shoots. …”

Supplementary file 1_An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study.... by Miguel Ángel Robles-Sánchez (21211703)

“…Lifestyle habits remained mostly unchanged, except for medication self-management and diet, whereas visits to nurses and other professionals in MS units significantly decreased. Physical health composite scores in the MS quality of life-54 questionnaire decreased, while the mental health composite scores remained unchanged. …”

Light avoidance requires the cGMP-dependent pathway in <i>P</i>. <i>pacificus</i>. by Kenichi Nakayama (2354653)

“…<p>(A) Blue light avoidance assay for light-unresponsive mutants that were isolated by forward genetic screening. These mutants had decreased light-induced avoidance response. (B) List of predicted causal genes. …”

Data Sheet 2_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf by Meiling Liu (390553)

“…Additionally, RT-qPCR results revealed decreased levels of VAV3 (vav guanine nucleotide exchange factor 3, a target of miR-499a-5p) and IGF1 (insulin like growth factor 1, a target of miR-576-5p) in the CSF samples of NB patients.…”

Supplementary Material for: DOT1L regulates cellular senescence during the progression from acute kidney injury to chronic kidney disease via the micro-222-5p/WNT9B signaling pathw... by figshare admin karger (2628495)

“…High-throughput miRNA sequencing was performed to analyze differential expression of miRNAs downstream of DOT1L, and DOT1L overexpression and dual luciferase reporter gene experiments were conducted to explore interactions among DOT1L, miR-222-5p, and WNT9B. Results: The results demonstrated that in vivo inhibition of DOT1L significantly reduced cellular senescence and improved renal tubular injury and interstitial fibrosis. …”

Table 1_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.xlsx by Meiling Liu (390553)

“…Additionally, RT-qPCR results revealed decreased levels of VAV3 (vav guanine nucleotide exchange factor 3, a target of miR-499a-5p) and IGF1 (insulin like growth factor 1, a target of miR-576-5p) in the CSF samples of NB patients.…”

Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”