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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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18641
Primer sequences used in this study.
Published 2025“…B1W (300 mg/kg/day) significantly increased bone mineral density and bone volume fraction, but decreased trabecular separation compared to the OVX group. …”
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18642
60 Hz-induced neural entrainment.
Published 2025“…Statistical significance for these inter-group comparisons was assessed using the Wilcoxon rank-sum test. …”
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18643
Systematic All-Hydrocarbon Stapling Analysis for Cecropin A Generates a Potent and Stable Antimicrobial Peptide
Published 2025“…By evaluating antimicrobial and hemolytic activities, CEC-2–9 with the <i>C</i>-terminus threonine and lysine being stapled was identified as the optimal one. It exerted significantly enhanced antibacterial potency with more severe bacterial membrane damage capacity. …”
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18644
Table 4_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18645
Supplementary file 1_Clinical application of combined anticoagulation therapy in anti-MDA5 antibody-positive associated interstitial lung disease-a retrospective study.docx
Published 2025“…Meanwhile, C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine Kinase (CK) levels decreased significantly. Also, the incidence of complications and acute exacerbation was lower in the combined group (P < 0.05). …”
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18646
Table 1_Quantitative relationships between elastic modulus of rod and biomechanical properties of transforaminal lumbar interbody fusion: a finite element analysis.docx
Published 2025“…When rod-E increased from 1 GPa to 10 GPa, ROM decreased by 10.4%–39.4%. Further increasing rod-E from 10 GPa to 110 GPa resulted in a 9.3%–17.4% reduction in ROM. …”
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18647
Supplementary Material for: Splice variant of retinal G-protein-coupled receptor deletion (RGR-d)-mediated dysregulation of autophagy increases the susceptibility to age-related ma...
Published 2024“…Beclin-1 and LC3II/I expression levels were significantly decreased and that of P62 was elevated in RGR-d cells after PA stimulation. …”
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18648
Table 3_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18649
Image2_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…Moreover, this GABA<sub>A</sub>R mediated Cl<sup>−</sup> flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA<sub>A</sub> β3 subunit knockdown. …”
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18650
Data Sheet 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatic...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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18651
Data Sheet 1_Impact of endurance training on mitochondrial H2O2 production and NRF2 levels in different rat organs.pdf
Published 2025“…The level of malondialdehyde, a marker of oxidative damage, did not increase in the examined tissues, except the lungs, where it even decreased. Superoxide dismutase 1 levels increased in the lung, brain, and skeletal muscle, but decreased in the heart and remained unchanged in the liver. …”
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18652
In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes
Published 2025“…The in vivo findings reinforced these results, demonstrating that <b>Pt1</b> significantly reduced tumor growth while exhibiting minimal systemic toxicity. …”
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18653
Table 3_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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18654
In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes
Published 2025“…The in vivo findings reinforced these results, demonstrating that <b>Pt1</b> significantly reduced tumor growth while exhibiting minimal systemic toxicity. …”
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18655
Data Sheet 1_Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy.pdf
Published 2025“…Key parameters of infection (IL-6, TNFa, D-dimer, CRP and CD4<sup>+</sup> T cell counts) were correlated (Spearman) with lipid concentrations at critical time points of infection and treatment.</p>Results<p>Sphingomyelins (SM) and lactosylceramides (LCER) increased during acute infection, returning to baseline during chronic infection; Hexosylceramides (HCER) increased throughout infection, being normalized with prolonged ART; Phosphatidylinositols (PI) and lysophosphatidylcholines (LPC) decreased with SIV infection and did not return to normal with ART; Phosphatidylethanolamines (PE), lysophosphatidylethanolamines (LPE) and phosphatidylcholines (PC) were unchanged by SIV infection, yet significantly decreased throughout ART. …”
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18656
Table 1_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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18657
Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…Moreover, this GABA<sub>A</sub>R mediated Cl<sup>−</sup> flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA<sub>A</sub> β3 subunit knockdown. …”
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18658
Image 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
Published 2025“…Among these targets, the differential expression of CASP7 significantly affected the progression-free survival of patients with CRC. …”
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18659
DataSheet1_UV-B induced flavonoid accumulation and related gene expression in blue- grained wheat at different periods of time.zip
Published 2024“…</p>Discussion<p>The expression of these genes decreased after early UV-B irradiation, but increased later. …”
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18660
Table 1_Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, paralle...
Published 2025“…Therapy adherence- and health literacy-related DRPs decreased significantly by ~60% and ~64%, respectively. …”