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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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18901
Image 3_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as...
Published 2024“…Iron content in cortical tissues was measured using a colorimetric assay.</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …”
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18902
Image_3_RETRACTED: Ammonia Scavenger Restores Liver and Muscle Injury in a Mouse Model of Non-alcoholic Steatohepatitis With Sarcopenic Obesity.TIF
Published 2025“…Hepatic infiltration of inflammatory cells and collagen deposition area were significantly decreased in HFD group by LOLA treatment. …”
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18903
Image_4_RETRACTED: Ammonia Scavenger Restores Liver and Muscle Injury in a Mouse Model of Non-alcoholic Steatohepatitis With Sarcopenic Obesity.TIF
Published 2025“…Hepatic infiltration of inflammatory cells and collagen deposition area were significantly decreased in HFD group by LOLA treatment. …”
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18904
Image_1_RETRACTED: Ammonia Scavenger Restores Liver and Muscle Injury in a Mouse Model of Non-alcoholic Steatohepatitis With Sarcopenic Obesity.TIF
Published 2025“…Hepatic infiltration of inflammatory cells and collagen deposition area were significantly decreased in HFD group by LOLA treatment. …”
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18905
Image_2_RETRACTED: Ammonia Scavenger Restores Liver and Muscle Injury in a Mouse Model of Non-alcoholic Steatohepatitis With Sarcopenic Obesity.TIF
Published 2025“…Hepatic infiltration of inflammatory cells and collagen deposition area were significantly decreased in HFD group by LOLA treatment. …”
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18906
Data Sheet 1_Qifuyin alleviates anxiety and depression in 3×Tg-AD mice by modulating neuroendocrine function.zip
Published 2025“…In the QFY-treated group, plasma CORT levels were significantly decreased, whereas FSH and LH levels were significantly increased. …”
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18907
Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway
Published 2024“…In BV2 cells, LPS treatment decreased expression of BDNF, IL-10, and Arg1, while BDNF overexpression (BDNF-OE) significantly reversed the inflammation-induced by LPS by repressing iNOS and TNF-α, while increasing IL-10 and Arg1. …”
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18908
Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma
Published 2025“…CD63 knockdown in ESCC cell lines resulted in a phenotype of decreased proliferative potential. …”
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18909
Table 1_Nanocarrier-mediated RNAi of CYP9E2 and CYB5R enhance susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx
Published 2025“…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9E2 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP92 genes. …”
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18910
Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway
Published 2025“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”
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18911
Data_Sheet_1_Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits.pdf
Published 2024“…A 60-day incubation experiment was conducted with four treatments: no fertilizer (CK), urea (U), urea with copper pyrazole (UC), and urea coated with copper pyrazole (SUC), to evaluate the changes about soil ammonia N (NH4+-N) and nitrate N (NO3−-N) levels as well as in soil microbial community throughout the whole incubation period. The results showed that copper pyrazole exhibited significantly higher inhibition rates on urease compared to other metal-pyrazole coordination compounds. …”
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18912
Table 1_Nanocarrier-mediated RNAi of CYP9A306 and CYB5R enhances susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx
Published 2025“…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9A306 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP9A306 genes. …”
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18913
Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s...
Published 2025“…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …”
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18914
Data Sheet 1_Stand structure influences understory plant diversity through soil factors: three afforestation types of Masson’s pine in the upper Yangtze River, China.docx
Published 2025“…In terms of stand structure, MCLMF significantly increased the opening degree (O), mingling index (M), and competition index (CI), while MLMF decreased CI but increased M. …”
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18915
Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX
Published 2024“…Only three bile acid metabolites, taurodeoxycholic acid, taurochenodeoxycholic acid, and deoxycholic acid, were significantly different between the ANLF1 and ANLF2 groups, increasing at first and then decreasing with the aggravation of liver injury. …”
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18916
<b>The Impact of Vitiligo on Pregnancy and Perinatal Outcome: A Systematic Review and Meta-analysis</b>
Published 2025“…Pregnant women with vitiligo had a significantly higher chance of spontaneous abortion (OR 1.26; 95% CI [1.17, 1.36]), but a significantly lower chance of cesarean delivery (OR 0.93; 95% CI [0.87, 0.99]) than pregnant women without vitiligo. …”
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18917
Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx
Published 2025“…After baicalein treatment, the proinflammatory cytokines (TNF-α, IL-1β), and anti-inflammatory cytokine (IL-10) has decreased. Additionally, high-dose of baicalein strongly reversed oxidative stress alterations caused by DSS, as evidenced by Fe<sup>2+</sup>, MDA, ROS significantly depleted, and MPO, SOD, GSH significantly increased. …”
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18918
Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
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18919
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Methods<p>In this study, a glutamate-induced oxidative stress damage model of R28 cells and a rat retinal injury model were established to investigate the effects of baicalin on oxidative stress damage to RGCs and try to elucidate the underlying mechanism.</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
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18920
Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx
Published 2025“…The regulatory mechanism of MrgC on UPR<sup>mt</sup> was further explored in N2a and 293T cells.</p>Results<p>Mice with bone cancer pain showed improved mRNA and protein levels of UPR<sup>mt</sup>-related molecules, increased MMP and ATP, decreased mitochondrial ROS levels in the spinal cord after receiving an intrathecal injection of BAM8-22. …”