Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant results » significant reductions (Expand Search), significant reduction (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant results » significant reductions (Expand Search), significant reduction (Expand Search)
-
18921
Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx
Published 2025“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”
-
18922
Table 3_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
-
18923
Mapping global urban inequality under climate change and its interaction with sustainable development
Published 2025“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”
-
18924
Image 1_The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells.tif
Published 2025“…E2F1 was identified as an upstream regulator of EIF4EBP1, with knockdown of E2F1 significantly decreasing EIF4EBP1 promoter activity and binding. …”
-
18925
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…Cell proliferation, migration, and angiogenesis were determined using CCK-8 assays, transwell assays, and tubule formation assays, respectively.</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
-
18926
Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx
Published 2025“…Signaling pathway involvement was examined using PI3K inhibitor LY294002, AKT activator SC79, and FOXO1 knockdown.</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …”
-
18927
Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx
Published 2025“…In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
-
18928
Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx
Published 2025“…In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
-
18929
Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
-
18930
Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
-
18931
Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
-
18932
Image 2_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…However, the combined H1H1/AG+GG genotype was significantly more frequent in women with GDM than in the control group. …”
-
18933
Table1_Biomechanical effects of different mandibular movements and torque compensations during mandibular advancement with clear aligners: a finite element analysis.DOCX
Published 2024“…Different torque compensation angles (0°, 1°, 2°, and 3°) were applied to the mandibular central incisor.</p>Results<p>When the mandibular advancement was equal to or slightly excessed the occlusal opening distance, stress on the posterior PDL decreased and became more evenly distributed. …”
-
18934
Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx
Published 2025“…In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
-
18935
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
-
18936
Data Sheet 1_Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection.pdf
Published 2025“…</p>Results<p>TLR7 levels were higher in patients with mild disease compared to those with moderate disease and decreased over time. …”
-
18937
Table 1_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
-
18938
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Methods<p>In this study, a glutamate-induced oxidative stress damage model of R28 cells and a rat retinal injury model were established to investigate the effects of baicalin on oxidative stress damage to RGCs and try to elucidate the underlying mechanism.</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
-
18939
Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…However, the combined H1H1/AG+GG genotype was significantly more frequent in women with GDM than in the control group. …”
-
18940
Table 2_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”