Supplementary Material for: Downregulation of Signal Transducer and Activator of Transcription 4 (STAT4) contributes to impaired osteogenic differentiation of human bone marrow ste... by figshare admin karger (2628495)

“…RNA samples from STAT4-overexpressing hBMSCs were analyzed by RNA-seq to identify differentially expressed genes (DEGs), followed by bioinformatics analyses to determine the pathways affected by STAT4. Results: STAT4 expression progressively decreases during the in vitro expansion of hBMSCs, concomitant with the loss of osteogenic differentiation potential. …”

DataSheet1_Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress.docx by Renyuan Wang (10921218)

“…Through pot experiments, we investigated how HRW affects plant growth, ion absorption, osmotic stress, oxidative stress, antioxidant enzyme levels, hormone levels, and root endophytic bacteria in strawberry seedlings under salt stress. The results showed that under 100 mM NaCl treatment, 50% and 100% HRW treatments significantly increased strawberry biomass by 0.29 g and 0.54g, respectively, wherein, 100% HRW significantly increased the shoot and root length by 15.34% and 24.49%, respectively. …”

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx by Shubin Wang (3105348)

“…The proliferation of intestinal stem cells (ISCs) was shown by BrdU and Olfm4 staining, and Lgr5-tdTomato mice were used for lineage tracing study.</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. …”

Image 2_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif by Si-Ting Huang (5591432)

“…Inhibition of TRPA1 or administration of recombinant IL-18 significantly reduced DNFB-induced itch behavior in Nlrp3-/- mice. …”

Image 1_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg by Shuting Hua (21264785)

“…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”

Table 8_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Image 1_Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis.tif by Dongzhi Liu (2747134)

“…In the HSE group, DC values were increased in the right thalamus, the left lingual gyrus, and the right hippocampus, while they were decreased in the left insula (all p < 0.001). In our HSE cohort, the NIHSS score was significantly associated with DC changes in the right thalamus (r = −0.282, p = 0.018), the left insula (r = −0.301, p = 0.011), the left lingual gyrus (r = −0.270, p = 0.024), and the right hippocampus (r = 0.238, p = 0.047). …”

Table 7_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Image 1_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Figure 2 from mTORC1-Driven Protein Translation Correlates with Clinical Benefit of Capivasertib within a Genetically Preselected Cohort of <i>PIK3CA</i>-Altered Tumors by Constance A. Sobsey (19373550)

“…Node size increases as the <i>P</i>-value decreases. <b>B,</b> Top 20 canonical pathways that are significantly differentially activated between clinical benefit (CB) and no clinical benefit (NCB) groups, based on assessment with Fisher’s exact test in Qiagen IPA. …”

Table 1_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Consort flow diagram of the participants. by Preeyaphorn Songsorn (21799601)

“…During flow incentive spirometry, stroke volume and heart rate significantly increased, while cardiac output significantly decreased compared to volume incentive spirometry and costal breathing exercises with sustained maximal inspiration throughout the 10 breathing cycles.…”

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx by Yulia Dwi Setia (21590591)

“…Body weight decreased from 6 to 11 dpi, with recovery after 12 dpi. …”

Table 11_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.xlsx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Table 10_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Data Sheet 1_Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survival.docx by Yanlin Wang (110566)

“…We performed FOXP3/activated caspase-3 double immunohistochemistry to characterize features of the labial salivary glands.</p>Results<p>The peripheral abundance of Treg cells from relapsing pSS patients was significantly contracted, especially in patients with high disease activity. …”

Table 1_Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.docx by Zhenru Guo (21811247)

“…Correlation analysis was employed to explore the associations between sulcal depth, functional connectivity, and the severity of clinical symptoms in individuals with schizophrenia with auditory verbal hallucinations.</p>Results<p>Schizophrenia patients with auditory verbal hallucinations exhibited significantly increased sulcal depth in left hemispheric regions including the lingual gyrus, cingulate gyrus, pericalcarine cortex, parahippocampal gyrus, superior frontal gyrus, cuneus, and precuneus, whereas decreased sulcal depth was observed in right hemispheric regions encompassing the superior parietal gyrus, superior frontal gyrus, lingual gyrus, lateral occipital cortex, fusiform gyrus, postcentral gyrus, middle frontal gyrus, precentral gyrus, inferior temporal gyrus, precuneus, and parahippocampal gyrus compared to schizophrenia patients without auditory verbal hallucinations. …”

Table 9_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”

Table 4_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx by Zeyi Lv (19344178)

“…Review Manager 5.4 software was used for analysis, and standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated under a random-effects model.</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”